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44669 cwo

44669

cwo

clockwork orange

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition clockwork orange

研究结论

Date Results Publications
2017-05-06 14:20:00 Here we demonstrate that the transcription factor CLOCKWORK ORANGE (CWO) antagonizes CLK-CYC E-box binding, thus enhancing the removal of CLK-CYC from E-boxes to maintain transcriptional repression. This process requires PER, which suggests that PER-TIM and CWO cooperate to maintain a transcriptionally repressed state by removing CLK-CYC from E-boxes 27814361
2010-01-21 00:00:00 findings suggest that Clockwork Orange (CWO) acts preferentially in the late night to help terminate CLK-CYC-mediated transcription of direct target genes including cwo itself 17578907
2010-01-21 00:00:00 Results indicate that, in vivo, clockwork orange (CWO) modulates clock gene expression through both repressor and activator transcriptional functions. 18375860
2010-01-21 00:00:00 identification of novel clock gene candidates including clockwork orange (cwo), a transcriptional repressor belonging to the basic helix-loop-helix ORANGE family[ 17578908

名称对应

Type IDs
Synonymous AAF24476.1, CG17100, CWO, Cwo, Dmel\CG17100, GM05287, bHLHe49, dcwo, mel_cwo
Gene
UniProtKB-ID: CWO_DROME, Q8MRI9_DROME
UniprotKB: Q9VGZ5, Q8MRI9
UniParc: UPI000007559C, UPI0000077B92
EMBL: AF203477, AY119588, AE014297, BT099842
EnsemblGenome: FBgn0259938
KO: dme:Dmel_CG17100
Nucleutide sequences
EMBL-CDS: AAF54527.2, AAF24476.1, ACW83550.1, AFH06343.1, AAM50242.1, AFH06342.1
Gene_ORFName: CG17100, CG17100, Dmel_CG17100
EnsemblGenome_TRS: FBtr0082246, FBtr0305151, FBtr0305152
Protein sequencees
EnsemblGenome_PRO: FBpp0081723, FBpp0293682, FBpp0293681
RefSeq: NP_001247025.1, NP_001247024.1, NP_524775.1
Others
UniRef100: UniRef100_Q9VGZ5
UniRef90: UniRef90_Q9VGZ5
UniRef50: UniRef50_Q9VGZ5
UniGene: Dm.11736

全选

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