| Type | Description |
|---|---|
| Definition | complement component 5a receptor 2 |
| Date | Results | Publications |
|---|---|---|
| 2014-10-04 12:39:00 | C5aR and C5L2, but not C3aR, are expressed on CD11b-positive leukocytes in islet preparations | 22099750 |
| 2010-01-21 00:00:00 | A C5aR isoform expressed by glia and neurons is regulated by NA and exerts anti-inflammatory functions. Changes in C5aR isoform levels in diseased brain could therefore contribute to the progression of inflammatory damage. | 15715664 |
| 2010-01-21 00:00:00 | data provide the first evidence for a role for C5a receptor C5L2 in balancing the biological responses to Complement 5a | 15784721 |
| 2010-01-21 00:00:00 | C5L2 appears to bind complement factor C5a and its C-terminal cleavage product C5a des Arg by different mechanisms, and, unlike C5a receptor (C5aR), C5L2 uses critical residues in its N-terminal domain for binding only to C5a des Arg. | 17158873 |
| 2010-01-21 00:00:00 | C5L2 is a highly regulated scavenger receptor for C5a and C5a-des-Arg(74) | 17068344 |
| Type | IDs |
|---|---|
| Synonymous | C5L2, Gpr77 |
| Gene |
UniProtKB-ID:
C5AR2_RAT,
Q5XPY4_RAT
UniprotKB:
Q695P6,
Q5XPY4
UniParc:
UPI000044D14B,
UPI0000401813
EMBL:
AY600435,
AY741660
Ensembl:
ENSRNOG00000049028
KO:
rno:445269
|
| Nucleutide sequences |
EMBL-CDS:
AAT12287.1,
AAU89282.1
Ensembl_TRS:
ENSRNOT00000071576
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000067721
RefSeq:
XP_006228415.1,
XP_006228414.1,
NP_001003710.3
|
| Others |
UniRef100:
UniRef100_Q5XPY4,
UniRef100_Q695P6
UniRef90:
UniRef90_Q695P6
UniRef50:
UniRef50_Q695P6
UniGene:
Rn.127117
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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