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444984 Dnmt3a

444984

Dnmt3a

DNA methyltransferase 3 alpha

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition DNA methyltransferase 3 alpha

研究结论

Date Results Publications
2021-02-20 13:30:00 DNMT3a in the hippocampal CA1 is crucial in the acquisition of morphine self-administration in rats. 30950138
2019-05-04 11:49:00 our results highlight miR-369-5p mediated DNMT3A epigenetic silencing of Patched1 as a mechanism of fibroblast proliferation in cardiac fibrosis 30114436
2018-11-17 11:56:00 Peripheral nerve injury increases expression of the DNA methyltransferase DNMT3a in the injured DRG neurons via the activation of the transcription factor octamer transcription factor 1. Blocking this increase prevents nerve injury-induced methylation of the voltage-dependent potassium (Kv) channel subunit Kcna2 promoter region and rescues Kcna2 expression in the injured DRG and attenuates neuropathic pain. 28270689
2018-10-27 10:40:00 DNMT3A level was upregulated and negatively correlated with miR-200b expression in fibrosis tissues and cardiac fibroblasts. Our results provide a basis for understanding the molecular mechanism by which DNMT3A and miR-200b, in combination with rapamycin, upregulates autophagic activity. 29786779
2018-09-08 10:05:00 that increased dorsal horn DNMT3a contributes to bone cancer pain through silencing dorsal horn Kv1.2 expression 29056068

名称对应

Type IDs
Gene
UniProtKB-ID: DNM3A_RAT
UniprotKB: Q1LZ53
UniParc: UPI000042B0B1, UPI00001C979D
EMBL: BN000396, BN000395
Ensembl: ENSRNOG00000026649
KO: rno:444984
Nucleutide sequences
EMBL-CDS: CAE52318.1, CAE52317.1
Ensembl_TRS: ENSRNOT00000047210, ENSRNOT00000089093
Protein sequencees
Ensembl_PRO: ENSRNOP00000069441, ENSRNOP00000046524
RefSeq: XP_017449755.1, XP_017449757.1, XP_017449756.1, NP_001003958.1, NP_001003957.1
Others
UniRef100: UniRef100_Q1LZ53
UniRef90: UniRef90_O88508
UniRef50: UniRef50_Q9Y6K1
UniGene: Rn.92659

全选

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研究热度

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