dtl.L - denticleless E3 ubiquitin protein ligase homolog L homeolog-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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444035 dtl.L

基因描述

Type	Description
Definition	denticleless E3 ubiquitin protein ligase homolog L homeolog

研究结论

Date	Results	Publications
2014-12-20 12:33:00	CRL4(Cdt2) targets thymine DNA glycosylase (TDG), a base excision repair enzyme that is involved in DNA demethylation	24947512

名称对应

Type	IDs
Synonymous	cdt2, cdt2-b, dcaf2, dtl, dtl-b, l2dtl, ramp
Gene	UniProtKB-ID: DTLB_XENLA UniprotKB: Q6GPU3 UniParc: UPI00003B5787 EMBL: BC073015 KO: xla:444035
Nucleutide sequences	EMBL-CDS: AAH73015.1
Protein sequencees	RefSeq: NP_001085609.1
Others	UniRef100: UniRef100_Q6GPU3 UniRef90: UniRef90_Q6GPU3 UniRef50: UniRef50_Q9NZJ0 UniGene: Xl.34158

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mRNA

Protein

UniprotKB

Description

Refseq

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Location

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Pubmed编号	文献信息	发表日期	相关基因
24947512	Thymine DNA glycosylase is a CRL4Cdt2 substrate. J. Biol. Chem. Tamara J Slenn , Benjamin Morris , Courtney G Havens , Robert M Freeman , Tatsuro S Takahashi , Johannes C Walter	2014-08-15	-
23607668	Proteolysis of Xenopus Cip-type CDK inhibitor, p16Xic2, is regulated by PCNA binding and CDK2 phosphorylation. Cell Div Xi-Ning Zhu , Dong Hyun Kim , Horng-Ru Lin , Varija N Budhavarapu , Herbert B Rosenbaum , Paul R Mueller , P Renee Yew	2013-04-22	-
20606006	The CRL4Cdt2 ubiquitin ligase mediates the proteolysis of cyclin-dependent kinase inhibitor Xic1 through a direct association with PCNA. Mol. Cell. Biol. Dong Hyun Kim , Varija N Budhavarapu , Carlos R Herrera , Hyung Wook Nam , Yu Sam Kim , P Renee Yew	2010-09-01	-
19595719	Docking of a specialized PIP Box onto chromatin-bound PCNA creates a degron for the ubiquitin ligase CRL4Cdt2. Mol Cell Courtney G Havens , Johannes C Walter	2009-07-10	-
16949367	A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1. Mol. Cell Jianping Jin , Emily E Arias , Jing Chen , J Wade Harper , Johannes C Walter	2006-09-01	ddb1, dtl, dtl, DCAF7, COPS6, COPS5, ERCC8, DCAF12L1, DCAF8L1, DDB1, DDB2, WDTC1, DCAF12, DCAF13, DCAF4, GPS1, DCAF12L2, DCAF8, COPS7A, COPS4, DTL, DCAF16, PHIP, DET1, AMBRA1, DCAF6, RFWD2, COPS7B, DDA1, DCAF10, DCAF17, DCAF11, CDT1, CUL4B, CUL4A, COPS3, DCAF5, DCAF15, COPS2, VPRBP
12477932	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team	2002-12-24	-
12454917	Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Dev. Dyn. Steven L Klein , Robert L Strausberg , Lukas Wagner , Joan Pontius , Sandra W Clifton , Paul Richardson	2002-12-01	Rpl28, Uqcrc1, cyp2a6, cyp4b1.2, cyp4b1, LOC100036773, cyp17a1, cyp1a1, mpst, cct5b, mlh1, efha1, cox7a2-b, rraga, wbp2, aldh4a1, usp3, ints7, nkiras1, bbof1, fam160b1, emilin2, gas7, LOC100036792, qsox1, cacul1, LOC100036795, LOC100036796, LOC100036797, slc1a4, tsga14, LOC100036800, xab2, haus6, LOC100036803, taf5, golph3l-b, et-3, mex3c, plin1, ttc7b, diexf, slc2a14, tbc1d24.1, il-8, mrpl38, cytl1, LOC100036818, sgf29, LOC100036820, dbib, timm8b-b, LOC100036823, LOC100036824, rgs1, LOC100036826, ndfip1, LOC100036828, LOC100036829, admp2, LOC100036831, rasl10b, mks1, eif2d, dcaf5, gse1, LOC100036837, brd3, rere, csnk1g3, pip4k2a, tdrd5, gpank1, sin3b, LOC100036845, hk2, kiz, mob2.2, ap1b1, mfap3, LOC100036851, e2f1, rpa2-b, LOC100036854, chtf8, btn2a2, lman2l, h2afy, LOC100036859, LOC100036860, tmem214-b, cecr5, rassf1, LOC100036864, LOC100036865, dnase1l1, aven, nop2, LOC100036869

研究热度

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