| Type | Description |
|---|---|
| Definition | Rho guanine nucleotide exchange factor (GEF) 15 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-14 12:06:00 | a substrate of Ephexin5, whose early-elevated expression in developing neurons may in part explain the mechanism by which plays seemingly opposing roles that depend on neuronal maturity. | 30485813 |
| 2017-09-16 12:23:00 | pathological elevation of Ephexin5 expression critically drives Abeta-induced memory impairment | 28346227 |
| 2017-09-02 10:26:00 | The data of this study support a model in which Ephexin5 serves a dual role in spinogenesis, acting both as a brake on overall spine outgrowth and as a necessary component in the site-specific formation of new spines | 28185854 |
| 2011-05-12 12:40:00 | Study identified a RhoA guanine nucleotide exchange factor, Ephexin5, which negatively regulates excitatory synapse development until EphrinB binding to the EphB receptor triggers Ephexin5 phosphorylation, ubiquitination, and degradation.[Ephexin5] | 21029865 |
| Type | IDs |
|---|---|
| Synonymous | D130071N09, D530030K12Rik, E5 |
| Gene |
UniProtKB-ID:
ARHGF_MOUSE
UniprotKB:
Q5FWH6
UniParc:
UPI0000193691,
UPI0000DA6C73
EMBL:
AK173061,
AL603662,
BC116343,
BC089365,
BC116344
Ensembl:
ENSMUSG00000052921
KO:
mmu:442801
|
| Nucleutide sequences |
EMBL-CDS:
AAI16344.1,
BAD32339.1,
AAI16345.1,
AAH89365.1
Ensembl_TRS:
ENSMUST00000065040,
ENSMUST00000108671
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000104311,
ENSMUSP00000067684
RefSeq:
XP_030101975.1,
XP_006533732.1,
XP_011247423.1,
XP_011247419.1,
XP_011247418.1,
XP_011247414.1,
NP_808234.2,
XP_006533727.1,
XP_011247424.1,
XP_030101974.1,
NP_001351701.1,
XP_011247422.1,
XP_011247420.1,
XP_011247421.1,
XP_017170132.1,
XP_030101973.1,
XP_011247417.1,
XP_011247416.1
|
| Others |
UniRef100:
UniRef100_Q5FWH6
UniRef90:
UniRef90_Q5FWH6
UniRef50:
UniRef50_Q5FWH6
UniGene:
Mm.376147
CCDS:
CCDS24873.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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