| Type | Description |
|---|---|
| Definition | leiomodin 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 10:16:00 | Disruption of cardiac thin filament assembly arising from a mutation in LMOD2: A novel mechanism of neonatal dilated cardiomyopathy. | 31517052 |
| 2017-09-09 11:30:00 | Crystal Structure of Leiomodin 2 in Complex with Actin | 28834725 |
| 2016-06-28 11:49:00 | The mutation reduced binding affinity for both Lmod2 and Tmod1. The effect of the K15N mutation on Tpm1.1 binding to Lmod2 and Tmod1 provides a molecular rationale for the development of familial dilated cardiomyopathies . | 26873245 |
| 2016-05-14 12:35:00 | The C-terminal extension of Lmod2 and C terminal of Tmod1 are sufficient to produce a filament nucleator. | 26370058 |
| 2016-01-30 11:07:00 | Complementary functional studies suggest that the binding of Lmod2 stimulates ATP hydrolysis and accelerates actin nucleation and polymerization. | 26417072 |
| Type | IDs |
|---|---|
| Synonymous | C-LMOD, CLMOD |
| Gene |
UniProtKB-ID:
LMOD2_HUMAN
UniprotKB:
Q6P5Q4
UniParc:
UPI00015E0F9D,
UPI0001572CCA,
UPI00015E0F9C
EMBL:
BC062765,
CH236947,
BC017911
Ensembl:
ENSG00000170807
KO:
hsa:442721
|
| Nucleutide sequences |
EMBL-CDS:
EAL24334.1,
AAH17911.1,
AAH62765.1,
EAL24335.1
Ensembl_TRS:
ENST00000458573
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000411932
RefSeq:
NP_997046.1
|
| Others |
UniRef100:
UniRef100_Q6P5Q4
UniRef90:
UniRef90_Q6P5Q4
UniRef50:
UniRef50_Q6P5Q4
UniGene:
Hs.592260
CCDS:
CCDS47693.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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