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441549 CDNF

441549

CDNF

cerebral dopamine neurotrophic factor

protein-coding

Homo sapiens

基因描述

Type Description
Definition cerebral dopamine neurotrophic factor

研究结论

Date Results Publications
2020-02-15 12:43:00 Cerebral dopamine neurotrophic factor gene expression was significantly reduced in stroke patients relative to control subjects. 31744764
2018-09-29 12:05:00 Polymorphisms in CDN,F identified in a Han Chinese population, were associated with increased susceptibility to schizophrenia. 29298719
2018-06-30 11:50:00 In various animal models of Parkinson Disease, CDNF is efficient in protecting and repairing dopaminergic neurons, and it inhibits endoplasmic reticulum stress, euroinflammation, and apoptosis. 28337696
2017-09-16 11:49:00 The results showed that AAV8-CDNF administration significantly improved the motor function and increased the tyrosine hydroxylase (TH) levels in Parkinson's disease rats with mild lesions (2 weeks post lesion), but it had limited therapeutic effects in rats with severe lesions (5 weeks post lesion). 28622392
2016-04-02 10:29:00 Results suggest that CDNF treatment selectively enhances long-term memory consolidation 25975173

名称对应

Type IDs
Synonymous ARMETL1
Gene
UniProtKB-ID: CDNF_HUMAN
UniprotKB: Q49AH0
UniParc: UPI0000051CF6, UPI00001F8BAC
EMBL: CH471072, BC133044, BC133042, BC037872, AK301259
Ensembl: ENSG00000185267
KO: hsa:441549
Nucleutide sequences
EMBL-CDS: BAG62825.1, EAW86264.1, AAI33045.1, AAI33043.1, AAH37872.1
Ensembl_TRS: ENST00000378442, ENST00000465530
Protein sequencees
Ensembl_PRO: ENSP00000367703, ENSP00000419395
RefSeq: NP_001025125.2, XP_011517790.1
Others
UniRef100: UniRef100_Q49AH0
UniRef90: UniRef90_Q49AH0
UniRef50: UniRef50_Q49AH0
UniGene: Hs.559067
CCDS: CCDS31148.1

全选

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研究热度

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