Type | Description |
---|---|
Definition | aldo-keto reductase family 1 member B15 |
Date | Results | Publications |
---|---|---|
2016-05-14 11:26:00 | Amino acid substitutions clustered in loops A and C result in a smaller more hydrophobic and more rigid active site in AKR1B15 compared with the AKR1B10 pocket, consistent with distinct substrate specificity and narrower inhibitor selectivity for AKR1B15. | 26222439 |
2015-05-23 11:44:00 | AKR1B15.2 localizes to the cytosol and displays no enzymatic activity with the substrates tested. | 25577493 |
2014-05-07 15:01:00 | human sperm possess an aldo-keto reductase on their membrane surface and are thus enzymatically protected against reactive aldehyde species both in the male and female reproductive tract | 22970857 |
2012-03-20 11:46:00 | Strong candidate gene for mitochondrial disease, based on recessive mutations detected in infantile patients | 22277967 |
2011-08-27 10:37:00 | AKR1B15 and Akr1b16 genes are expressed as functional proteins in human and murine tissues | 21276782 |
Type | IDs |
---|---|
Synonymous | AKR1B10L, AKR1B10L, AK1R1B7, AKR1R1B7 |
Gene |
UniProtKB-ID:
AK1BF_HUMAN
UniprotKB:
C9JRZ8
UniParc:
UPI00004193E1,
UPI00000492EE
EMBL:
CH471070,
AC078847
Ensembl:
ENSG00000227471
KO:
hsa:441282
|
Nucleutide sequences |
EMBL-CDS:
EAW83819.1
Ensembl_TRS:
ENST00000423958,
ENST00000652743,
ENST00000457545
|
Protein sequencees |
Ensembl_PRO:
ENSP00000397009,
ENSP00000389289,
ENSP00000498877
RefSeq:
NP_001074007.2,
NP_001354751.1,
NP_001354749.1,
NP_001354750.1,
XP_016867713.1
|
Others |
UniRef100:
UniRef100_C9JRZ8
UniRef90:
UniRef90_O60218
UniRef50:
UniRef50_O60218
UniGene:
Hs.729418
CCDS:
CCDS47715.2
|
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Refseq |
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