例如:"NBL1", "4681", "drought"
收藏
441282 AKR1B15

441282

AKR1B15

aldo-keto reductase family 1 member B15

protein-coding

Homo sapiens

基因描述

Type Description
Definition aldo-keto reductase family 1 member B15

研究结论

Date Results Publications
2016-05-14 11:26:00 Amino acid substitutions clustered in loops A and C result in a smaller more hydrophobic and more rigid active site in AKR1B15 compared with the AKR1B10 pocket, consistent with distinct substrate specificity and narrower inhibitor selectivity for AKR1B15. 26222439
2015-05-23 11:44:00 AKR1B15.2 localizes to the cytosol and displays no enzymatic activity with the substrates tested. 25577493
2014-05-07 15:01:00 human sperm possess an aldo-keto reductase on their membrane surface and are thus enzymatically protected against reactive aldehyde species both in the male and female reproductive tract 22970857
2012-03-20 11:46:00 Strong candidate gene for mitochondrial disease, based on recessive mutations detected in infantile patients 22277967
2011-08-27 10:37:00 AKR1B15 and Akr1b16 genes are expressed as functional proteins in human and murine tissues 21276782

名称对应

Type IDs
Synonymous AKR1B10L, AKR1B10L, AK1R1B7, AKR1R1B7
Gene
UniProtKB-ID: AK1BF_HUMAN
UniprotKB: C9JRZ8
UniParc: UPI00004193E1, UPI00000492EE
EMBL: CH471070, AC078847
Ensembl: ENSG00000227471
KO: hsa:441282
Nucleutide sequences
EMBL-CDS: EAW83819.1
Ensembl_TRS: ENST00000423958, ENST00000652743, ENST00000457545
Protein sequencees
Ensembl_PRO: ENSP00000397009, ENSP00000389289, ENSP00000498877
RefSeq: NP_001074007.2, NP_001354751.1, NP_001354749.1, NP_001354750.1, XP_016867713.1
Others
UniRef100: UniRef100_C9JRZ8
UniRef90: UniRef90_O60218
UniRef50: UniRef50_O60218
UniGene: Hs.729418
CCDS: CCDS47715.2

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员