| Type | Description |
|---|---|
| Definition | fusilli |
| Date | Results | Publications |
|---|---|---|
| 2020-06-20 10:46:00 | Caz is a Drosophila homologue of FUS, which is one of the genes causing amyotrophic lateral sclerosis (ALS). The novel roles for Caz and Aub demonstrated herein using the Caz-knockdown fly will contribute to a deeper understanding of the pathogenesis of ALS. | 30578769 |
| 2019-12-07 10:09:00 | arginine residues in the C-terminal low-complexity domain are also required for maturation of FUS in cellular stress granules. | 30021151 |
| 2019-02-09 11:27:00 | Self-assembly of FUS through its low-complexity domain contributes to neurodegeneration in frontotemporal dementia-amyotrophic lateral sclerosis Drosophila model. | 29425337 |
| 2019-01-19 12:17:00 | Using a Drosophila model of FUS-ALS, we corroborate that induction of autophagy significantly increases survival. | 29358088 |
| 2018-11-10 10:17:00 | data show that mitochondrial impairment is a critical early event in FUS proteinopathy, and provide insights into the pathogenic mechanism of FUS-induced neurodegeneration. | 30249657 |
| Type | IDs |
|---|---|
| Synonymous | CG8205, Dmel\CG8205, E(cact[E10])7, cg8205 |
| Gene |
UniProtKB-ID:
FUSIL_DROME,
E1JH76_DROME,
E2QCE8_DROME,
A0A0B4K880_DROME
UniprotKB:
Q9BJZ5,
E1JH76,
E2QCE8,
A0A0B4K880
UniParc:
UPI000237F4E9,
UPI000007D94D,
UPI0000077ABF,
UPI0001C0004F,
UPI000007FBE2,
UPI000000BF9C
EMBL:
BT023793,
AY052064,
BT003299,
BT025963,
AE013599,
AF321979
EnsemblGenome:
FBgn0023441
KO:
dme:Dmel_CG8205
|
| Nucleutide sequences |
EMBL-CDS:
ABG02207.1,
AAK15280.1,
AAK93488.1,
AAO25059.1,
AAM70980.1,
AAM70981.1,
AAF58117.1,
AAM70983.1,
AAM70984.1,
AAZ41802.1,
ACZ94433.1,
AAM70982.1,
AFH08101.1
Gene_ORFName:
CG8205,
Dmel_CG8205,
CG8205,
Dmel_CG8205,
CG8205,
Dmel_CG8205,
CG8205
EnsemblGenome_TRS:
FBtr0087346,
FBtr0087345,
FBtr0087347,
FBtr0087344,
FBtr0087343,
FBtr0087348,
FBtr0302330,
FBtr0087344,
FBtr0087343,
FBtr0087346,
FBtr0306648
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0086476,
FBpp0086480,
FBpp0086477,
FBpp0086481,
FBpp0086478,
FBpp0086479,
FBpp0291536,
FBpp0086476,
FBpp0086479,
FBpp0086477,
FBpp0297603
RefSeq:
NP_001163161.1,
NP_725482.1,
NP_001246347.1,
NP_725480.1,
NP_725479.1,
NP_524691.1,
NP_725481.1,
NP_725483.1
|
| Others |
UniRef100:
UniRef100_E1JH76,
UniRef100_Q9BJZ5
UniRef90:
UniRef90_E1JH76,
UniRef90_Q9BJZ5
UniRef50:
UniRef50_Q9BJZ5
UniGene:
Dm.7727
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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