| Type | Description |
|---|---|
| Definition | coiled-coil domain containing 88C |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:29:00 | The Daple-CK1epsilon complex regulates Dvl2 phosphorylation and canonical Wnt signaling. | 32888647 |
| 2020-10-24 14:09:00 | DAPLE protein inhibits nucleotide exchange on Galphas and Galphaq via the same motif that activates Galphai. | 31949046 |
| 2020-10-24 14:06:00 | Two Isoforms of the Guanine Nucleotide Exchange Factor, Daple/CCDC88C Cooperate as Tumor Suppressors. | 31431650 |
| 2020-08-13 18:50:00 | Fusion driven JMML: a novel CCDC88C-FLT3 fusion responsive to sorafenib identified by RNA sequencing. | 31511612 |
| 2020-01-11 11:35:00 | DAPLE and MPDZ function as cooperative partners at apical junctions. | 31268831 |
| Type | IDs |
|---|---|
| Synonymous | DAPLE, HKRP2, HYC1, KIAA1509, SCA40 |
| Gene |
UniProtKB-ID:
DAPLE_HUMAN,
B4DZB8_HUMAN
UniprotKB:
Q9P219,
B4DZB8
UniParc:
UPI00006C1440,
UPI00017A858B,
UPI00006C1443,
UPI0000407FC6
EMBL:
AL133153,
BC028565,
AL135818,
AL833046,
AB040942,
AK302839,
BX248302,
BC035914,
CQ719279
Ensembl:
ENSG00000015133
KO:
hsa:440193
|
| Nucleutide sequences |
EMBL-CDS:
CAH10602.1,
AAH35914.1,
CAD62629.1,
AAH28565.2,
BAA96033.2,
BAG64030.1
Ensembl_TRS:
ENST00000389857
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000374507
RefSeq:
XP_016876825.1,
NP_001073883.2,
XP_016876826.1,
XP_011535098.1,
XP_005267748.1,
XP_016876824.1
|
| Others |
UniRef100:
UniRef100_Q9P219
UniRef90:
UniRef90_Q9P219
UniRef50:
UniRef50_Q9P219
UniGene:
Hs.525536
CCDS:
CCDS45151.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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