| Type | Description |
|---|---|
| Definition | Phosphatase and tensin homolog |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 12:21:00 | Our findings identify a novel PTEN/dPLCXD pathway that controls PtdIns(4,5)P2 levels on endosomes. They also point to a potential new strategy for the treatment of Lowe syndrome. | 31118240 |
| 2018-08-18 11:41:00 | Here we show that PTEN mutation impacts and Lgl protein levels also in Drosophila. Moreover, we demonstrate that PI3K activation is not sufficient to trigger tumourigenesis, while aduanyu1531 promotes hyperplastic growth of the neuroepithelium and a noticeable expansion of the type II neuroblasts. | 29445734 |
| 2016-12-17 10:52:00 | Ectopic expression of dPTEN (a phosphatase and tensin homologue) in the fat body prolongs fruit fly life. | 26318059 |
| 2016-04-16 10:55:00 | PTEN deficient cells proliferate under conditions of nutrient restriction. | 23853709 |
| 2013-08-31 10:13:00 | loss of the tumor suppressor PTEN disrupts cell rearrangements by preventing the lengthening of newly formed junctions that become unstable and keep on rearranging | 23707736 |
| Type | IDs |
|---|---|
| Synonymous | CG5671, DPTEN, Dmel\CG5671, PTEN, PTEN3, dPTEN, dPten, dpten, pten |
| Gene |
UniProtKB-ID:
Q9V3L4_DROME,
Q7KMQ6_DROME,
Q9Y0B6_DROME
UniprotKB:
Q9V3L4,
Q7KMQ6,
Q9Y0B6
UniParc:
UPI000007DC02,
UPI00000801A3,
UPI0000083CFD
EMBL:
AF161257,
AF161259,
AE014134,
AF144232,
AF201904,
BT025053
EnsemblGenome:
FBgn0026379
KO:
dme:Dmel_CG5671
|
| Nucleutide sequences |
EMBL-CDS:
AAF52889.1,
AAF23235.1,
AAD45364.1,
AAF52887.2,
AAN10731.1,
AAN10732.2,
AAF08382.1,
ABE73224.1,
AAF52888.1,
ACZ94222.1,
AAD45362.1,
AAN10730.1
Gene_ORFName:
Dmel_CG5671,
CG5671,
CG5671,
Dmel_CG5671,
Dmel_CG5671,
CG5671
EnsemblGenome_TRS:
FBtr0089905,
FBtr0089901,
FBtr0089900,
FBtr0301521,
FBtr0089904,
FBtr0300562,
FBtr0089902
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0088840,
FBpp0088844,
FBpp0088839,
FBpp0290736,
FBpp0289789,
FBpp0088843,
FBpp0088841
RefSeq:
NP_599148.1,
NP_001162933.1,
NP_477423.1,
NP_599147.1,
NP_599149.1,
NP_477424.1,
NP_477422.2
|
| Others |
UniRef100:
UniRef100_Q9Y0B6,
UniRef100_Q7KMQ6,
UniRef100_Q9V3L4
UniRef90:
UniRef90_Q9Y0B6,
UniRef90_Q7KMQ6
UniRef50:
UniRef50_Q9Y0B6,
UniRef50_Q7KMQ6
UniGene:
Dm.1417
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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