| Type | Description |
|---|---|
| Definition | AMP-activated protein kinase alpha subunit |
| Date | Results | Publications |
|---|---|---|
| 2021-01-23 13:04:00 | A conserved role for AMP-activated protein kinase in NGLY1 deficiency. | 33315951 |
| 2018-05-05 12:02:00 | Data (including data from transgenic flies) suggest that SNF1A is involved in neuroprotection in this species; AMPK activation in glia (but not neurons) reduces severity of ionic disruption and prolongs recovery of electrical activity in brains of flies in starvation-induced anoxia. | 28916374 |
| 2017-06-10 11:26:00 | AMPK can function outside of its canonical nutrient-sensing role in specific developmental contexts. | 27729213 |
| 2013-04-13 11:35:00 | The significance of these findings is that AMPK is important in the regulation of glucagon signaling, suggesting that the organization of metabolic networks is highly conserved and that AMPK plays a prominent role in these networks. | 22798489 |
| 2013-01-05 10:55:00 | Loss of AMPK activity exacerbates neuronal loss and associated phenotypes in parkin and LRRK transgenic flies. | 23055502 |
| Type | IDs |
|---|---|
| Synonymous | AK, AMPK, AMPK-alpha, AmpKalpha, CG3051, DmAMPK alpha, Dmel\CG3051, EG:132E8.2, FBgn0023169, Gprk-4, Gprk4, SNF1A, SNF4A-a, ampk, ampkalpha, dAMPK, dAMPKa, dAMPKalpha, snf1A, snf1a |
| Gene |
UniProtKB-ID:
O18645_DROME
UniprotKB:
O18645
UniParc:
UPI000007E3B4
EMBL:
AL023893,
AE014298,
BT044168,
AF020309,
AF020310
EnsemblGenome:
FBgn0023169
KO:
dme:Dmel_CG3051
|
| Nucleutide sequences |
EMBL-CDS:
AAF45614.1,
AAN09043.1,
CAA19653.1,
ACH92233.1,
AAB71397.1,
AAS65245.1,
AAB71398.1
Gene_ORFName:
Dmel_CG3051,
CG3051
EnsemblGenome_TRS:
FBtr0070217,
FBtr0070218,
FBtr0070216
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0070209,
FBpp0070208,
FBpp0089374
RefSeq:
NP_996327.1,
NP_726730.1,
NP_477313.1
|
| Others |
UniRef100:
UniRef100_O18645
UniRef90:
UniRef90_O18645
UniRef50:
UniRef50_O18645
UniGene:
Dm.3013
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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