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43904 AMPKalpha

43904

AMPKalpha

AMP-activated protein kinase alpha subunit

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition AMP-activated protein kinase alpha subunit

研究结论

Date Results Publications
2021-01-23 13:04:00 A conserved role for AMP-activated protein kinase in NGLY1 deficiency. 33315951
2018-05-05 12:02:00 Data (including data from transgenic flies) suggest that SNF1A is involved in neuroprotection in this species; AMPK activation in glia (but not neurons) reduces severity of ionic disruption and prolongs recovery of electrical activity in brains of flies in starvation-induced anoxia. 28916374
2017-06-10 11:26:00 AMPK can function outside of its canonical nutrient-sensing role in specific developmental contexts. 27729213
2013-04-13 11:35:00 The significance of these findings is that AMPK is important in the regulation of glucagon signaling, suggesting that the organization of metabolic networks is highly conserved and that AMPK plays a prominent role in these networks. 22798489
2013-01-05 10:55:00 Loss of AMPK activity exacerbates neuronal loss and associated phenotypes in parkin and LRRK transgenic flies. 23055502

名称对应

Type IDs
Synonymous AK, AMPK, AMPK-alpha, AmpKalpha, CG3051, DmAMPK alpha, Dmel\CG3051, EG:132E8.2, FBgn0023169, Gprk-4, Gprk4, SNF1A, SNF4A-a, ampk, ampkalpha, dAMPK, dAMPKa, dAMPKalpha, snf1A, snf1a
Gene
UniProtKB-ID: O18645_DROME
UniprotKB: O18645
UniParc: UPI000007E3B4
EMBL: AL023893, AE014298, BT044168, AF020309, AF020310
EnsemblGenome: FBgn0023169
KO: dme:Dmel_CG3051
Nucleutide sequences
EMBL-CDS: AAF45614.1, AAN09043.1, CAA19653.1, ACH92233.1, AAB71397.1, AAS65245.1, AAB71398.1
Gene_ORFName: Dmel_CG3051, CG3051
EnsemblGenome_TRS: FBtr0070217, FBtr0070218, FBtr0070216
Protein sequencees
EnsemblGenome_PRO: FBpp0070209, FBpp0070208, FBpp0089374
RefSeq: NP_996327.1, NP_726730.1, NP_477313.1
Others
UniRef100: UniRef100_O18645
UniRef90: UniRef90_O18645
UniRef50: UniRef50_O18645
UniGene: Dm.3013

全选

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