| Type | Description |
|---|---|
| Definition | unc-13 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:18:00 | Unc13A and Unc13B contribute to the decoding of distinct sensory information in Drosophila. | 33771998 |
| 2021-03-20 13:26:00 | RIM-binding protein couples synaptic vesicle recruitment to release sites. | 32369542 |
| 2019-04-13 11:11:00 | Study in Drosophila identify Unc13A as a direct molecular target for presynaptic homeostatic potentiation (PHP) in experiments where Unc13A was delocalized from the presynaptic active zone (AZ) scaffolds. This mutant displayed sizable synaptic transmission but completely lacked PHP and AZ-remodeling. | 30842428 |
| 2019-02-02 11:45:00 | Study shows that ethanol regulates presynaptic activity and sedation through presynaptic unc13 proteins in drosophila. Study proposes that reducing Dunc13 activity, genetically or pharmacologically by ethanol binding to the C1 domain of Munc13-1/Dunc13, promotes a homeostatic response that leads to ethanol tolerance. | 29911175 |
| 2017-10-07 11:45:00 | Stable Positioning of Unc13 Restricts Fusion to Defined Release Sites to Promote Synchronous Neurotransmission | 28867551 |
| Type | IDs |
|---|---|
| Synonymous | CG2999, DUNC-13, Dmel\CG2999, Dunc-13, Dunc13, Munc-13, Munc-13/UNC-13, UNC-13, UNC-13-B, UNC13A, UNC13B, Unc-13, Unc13A, Unc13B, dUNC-13, dUnc-13, drunc13, dunc-13, l(4)ry16, unc |
| Gene |
UniProtKB-ID:
Q8IM87_DROME,
Q8IM86_DROME,
X2J9E1_DROME,
L0MPR2_DROME,
Q9V483_DROME,
H9XVP2_DROME
UniprotKB:
Q8IM87,
Q8IM86,
X2J9E1,
L0MPR2,
Q9V483,
H9XVP2
UniParc:
UPI0002A831B3,
UPI000007F082,
UPI00025911B9,
UPI00000849C7,
UPI00004ECEA0,
UPI00000849C8
EMBL:
AE014135
EnsemblGenome:
FBgn0025726
KO:
dme:Dmel_CG2999
|
| Nucleutide sequences |
EMBL-CDS:
AFH06786.1,
AAN06592.1,
AAN06593.1,
AHN58218.1,
AGB96565.1,
AAF59405.4,
AFH06787.1
Gene_ORFName:
CG2999,
Dmel_CG2999,
Dmel_CG2999,
CG2999,
CG2999,
Dmel_CG2999,
CG2999,
Dmel_CG2999,
CG2999,
Dmel_CG2999,
Dmel_CG2999,
CG2999
EnsemblGenome_TRS:
FBtr0308805,
FBtr0089245,
FBtr0089247,
FBtr0344971,
FBtr0334487,
FBtr0089246,
FBtr0308806
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0300962,
FBpp0088305,
FBpp0088307,
FBpp0311224,
FBpp0306555,
FBpp0088306,
FBpp0300963
RefSeq:
NP_726615.1,
NP_001245426.1,
NP_726614.2,
NP_651949.2,
NP_001245427.1,
NP_001259075.1,
NP_001284717.1
|
| Others |
UniRef100:
UniRef100_Q8IM86,
UniRef100_Q9V483,
UniRef100_L0MPR2,
UniRef100_Q8IM87,
UniRef100_H9XVP2,
UniRef100_X2J9E1
UniRef90:
UniRef90_Q9V483,
UniRef90_H9XVP2
UniRef50:
UniRef50_Q9V483,
UniRef50_H9XVP2
UniGene:
Dm.3358
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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