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43838 mGluR

43838

mGluR

metabotropic Glutamate Receptor

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition metabotropic Glutamate Receptor

研究结论

Date Results Publications
2020-07-18 12:20:00 loss of the conserved proline-rich PPXXF sequence on DmGluRA reduces Homer/DmGluRA associations and significantly reduces sleep amount. Thus, identifying a conserved mechanism of synaptic plasticity in Drosophila and demonstrating that the interaction of Homer with DmGluRA is necessary to promote sleep. 31418019
2020-05-02 12:58:00 mGluR signaling regulates sleep/wake in a manner that is relevant to the aging process. 31103635
2015-05-30 10:07:00 Drosophila master pacemaker neurons perceive both PDF and glutamate via PDFR and mGluRA G-protein coupled receptors that increase or decrease intracellular cAMP, respectively in response to light stimulus. 25268747
2010-01-21 00:00:00 Metabotropic glutamate receptor A (mGluRA) and fragile X mental retardation (Fmr) protein genetically interact in behavioral movement regulation. 18280750
2010-01-21 00:00:00 we report DmGluRA expression in most neuropile areas in both larvae and adults, but not in the lobes of the mushroom bodies 18303583

名称对应

Type IDs
Synonymous CAA67993.1_Dr, CG11144, DmGlu-A, DmGlu-RA, DmGluA, DmGluAR, DmGluR, DmGluRA, DmGluR[[A]], DmGlu[[A]]R, Dmel\CG11144, FBgn0019985, Glu-RA, GluR, dmGluRA, mGLuR, mGluRA
Gene
UniProtKB-ID: GRM_DROME, C5WLT4_DROME, L0MPZ9_DROME, X2JBI2_DROME
UniprotKB: P91685, C5WLT4, L0MPZ9, X2JBI2
UniParc: UPI0001AAF9C6, UPI0003E2C827, UPI00001245D3
EMBL: AE014135, BT088899, X99675
EnsemblGenome: FBgn0019985
KO: dme:Dmel_CG11144
Nucleutide sequences
EMBL-CDS: CAA67993.1, AAF59402.1, ACT09396.1, AGB96567.1, AGB96566.1, AHN58219.1
Gene_ORFName: CG11144, CG11144, Dmel_CG11144, Dmel_CG11144, CG11144, CG11144, Dmel_CG11144
EnsemblGenome_TRS: FBtr0332858, FBtr0089184, FBtr0332859, FBtr0089184, FBtr0332858, FBtr0344897
Protein sequencees
EnsemblGenome_PRO: FBpp0305080, FBpp0088248, FBpp0305081, FBpp0305080, FBpp0088248, FBpp0311208
RefSeq: NP_001259076.1, NP_524639.2, NP_001284718.1, NP_001259077.1
Others
UniRef100: UniRef100_C5WLT4, UniRef100_P91685, UniRef100_X2JBI2
UniRef90: UniRef90_C5WLT4, UniRef90_X2JBI2, UniRef90_P91685
UniRef50: UniRef50_P91685, UniRef50_C5WLT4, UniRef50_X2JBI2
UniGene: Dm.1789

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