| Type | Description |
|---|---|
| Definition | gawky |
| Date | Results | Publications |
|---|---|---|
| 2013-06-08 11:35:00 | This study demonistryed that GW182's gene silencing activity functions as a rheostat for PDFR signaling and thus profoundly impacts the circadian neural network and its response to environmental inputs. | 23583112 |
| 2013-04-06 11:31:00 | miRNA-mediated translational repression and degradation are mechanistically linked and are triggered through the interactions of GW182 with poly(A)-binding protein and deadenylases. | 23172285 |
| 2013-03-02 10:52:00 | Gawky plays a critical role in miRNA-mediated gene silencing. (Review) | 23224968 |
| 2013-02-23 11:54:00 | MicroRNAs utilize at least three distinct silencing pathways: GW182-mediated deadenylation and GW182-dependent and -independent repression of early translation initiation. | 23123195 |
| 2012-01-21 10:18:00 | Data demonstrate that in human and Drosophila melanogaster cells, the critical repressive features of both the N-terminal and C-terminal effector domains of GW182 proteins are Gly/Ser/Thr-Trp (G/S/TW) or Trp-Gly/Ser/Thr (WG/S/T) motifs. | 21984184 |
| Type | IDs |
|---|---|
| Synonymous | CG11484, CG31992, CG9905, Dmel\CG31992, GQ182, GW, GW182, Gw, Gw182, anon-EST:Posey205, dGW182, gw182 |
| Gene |
UniProtKB-ID:
GAWKY_DROME
UniprotKB:
Q8SY33
UniParc:
UPI0002945AC7,
UPI00029473AF,
UPI0000077C74
EMBL:
AE014135,
AY118860,
AY075429
EnsemblGenome:
FBgn0051992
KO:
dme:Dmel_CG31992
|
| Nucleutide sequences |
EMBL-CDS:
AAN06509.1,
AAL68245.1,
AAN06508.1,
AAF59323.2,
AAM50720.1,
AAF59322.2,
AAN06507.2,
AAX52511.2
Gene_ORFName:
CG31992
EnsemblGenome_TRS:
FBtr0089100,
FBtr0089101,
FBtr0310543,
FBtr0089097,
FBtr0310542,
FBtr0089096
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0088169,
FBpp0302679,
FBpp0088170,
FBpp0088165,
FBpp0302680,
FBpp0088166
RefSeq:
NP_726597.1,
NP_001014691.2,
NP_726601.1,
NP_726600.1,
NP_726596.1
|
| Others |
UniRef100:
UniRef100_Q8SY33
UniRef90:
UniRef90_Q8SY33
UniRef50:
UniRef50_Q8SY33
UniGene:
Dm.1403
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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