| Type | Description |
|---|---|
| Definition | legless |
| Date | Results | Publications |
|---|---|---|
| 2018-02-10 10:42:00 | The authors used CRISPR/Cas9 genome engineering of Drosophila legless (lgs) and human BCL9 and B9L to show that the C-terminus downstream of their adaptor elements is crucial for Wnt responses. | 28296634 |
| 2010-01-21 00:00:00 | Pygo and Lgs function in targeting Armadillo/beta-catenin to the nucleus, thus ensuring its availability to TCF during Wnt signalling. | 15208637 |
| 2010-01-21 00:00:00 | the PHD domain is required to link Drosophila Pygopus to Legless/beta-catenin and not to histone H3 | 19493659 |
| 2010-01-21 00:00:00 | Pygopus and legless provide essential transcriptional coactivator functions to armadillo/beta-catenin. | 16005293 |
| 2010-01-21 00:00:00 | Data show that human and Drosophila Pygo PHD fingers associate with their cognate HD1 domains from BCL9/Legless to bind specifically to the histone H3 tail methylated at lysine 4 (H3K4me). | 18498752 |
| Type | IDs |
|---|---|
| Synonymous | BCL9, CG2041, Dm Lgs, Dmel\CG2041, Lgl, Lgs |
| Gene |
UniProtKB-ID:
BCL9_DROME
UniprotKB:
Q961D9
UniParc:
UPI00000077A3
EMBL:
AY051651,
AE014135,
AF457205
EnsemblGenome:
FBgn0039907
KO:
dme:Dmel_CG2041
|
| Nucleutide sequences |
EMBL-CDS:
AAK93075.1,
AAF59345.2,
AAL91368.1
Gene_ORFName:
CG2041
EnsemblGenome_TRS:
FBtr0089111
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0088180
RefSeq:
NP_651922.1
|
| Others |
UniRef100:
UniRef100_Q961D9
UniRef90:
UniRef90_Q961D9
UniRef50:
UniRef50_Q961D9
UniGene:
Dm.1400
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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