| Type | Description |
|---|---|
| Definition | Rad23 |
| Date | Results | Publications |
|---|---|---|
| 2017-05-20 12:11:00 | Additional studies established that the increased toxicity upon mutating UbS2 stems from disrupting the autoprotective role that pathogenic ataxin-3 has against itself, which depends on the co-chaperone, DnaJ-1. Our data reveal a previously unrecognized balance between pathogenic and potentially therapeutic properties of the ataxin-3-Rad23 interaction; they highlight this interaction as critical for the toxicity of the S | 28158474 |
| 2016-08-20 12:12:00 | Through DnaJ-1, our data connect ataxin-3 and Rad23 to protective processes involved with protein folding rather than increased turnover of toxic polyQ species. | 26007638 |
| Type | IDs |
|---|---|
| Synonymous | CG1836, DHR23, Dmel\CG1836, RAD23, rad23 |
| Gene |
UniProtKB-ID:
Q9V3W9_DROME,
Q8IMB7_DROME
UniprotKB:
Q9V3W9,
Q8IMB7
UniParc:
UPI0000081696,
UPI00000849AA
EMBL:
AF132147,
AE014135
EnsemblGenome:
FBgn0026777
KO:
dme:Dmel_CG1836
|
| Nucleutide sequences |
EMBL-CDS:
AAF59352.1,
AAD33594.1,
AGB96542.1,
AAN06526.1
Gene_ORFName:
Dmel_CG1836,
CG1836,
CG1836,
Dmel_CG1836
EnsemblGenome_TRS:
FBtr0333679,
FBtr0089122,
FBtr0089121
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0088191,
FBpp0305835,
FBpp0088190
RefSeq:
NP_726561.1,
NP_001259052.1,
NP_651918.2
|
| Others |
UniRef100:
UniRef100_Q9V3W9
UniRef90:
UniRef90_Q9V3W9
UniRef50:
UniRef50_Q9V3W9
UniGene:
Dm.1397
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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