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43769 pan

43769

pan

pangolin

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition pangolin

研究结论

Date Results Publications
2020-04-04 11:10:00 We identify the conserved transcription factors Sox box protein 15 (Sox15) and Ftz transcription factor 1 (Ftz-f1) as genes controlled by dTcf/Pan involved in tumor development. In conclusion, this study reports a role for dTcf/Pan as a repressor of normal and oncogenic growth and identifies the genes inducing tumorigenesis downstream of dTcf/Pan. 31235567
2017-05-06 10:40:00 Requirement of Pangolin for transcriptional regulation of Wingless target genes.Pan regulates Wnt/Wg-responsive enhancers. 28369070
2015-11-21 10:26:00 The type of HMG and Helper sites is sufficient to direct activation or repression of Wnt regulated cis-regulatory modules, and protease digestion studies suggest that TCF/Pangolin adopts distinct conformations when bound to either HMG-Helper site pair 25144371
2015-01-31 12:41:00 The DNA binding ability of the C-clamp domain of pangolin is functionally important for patterning the drosophila embryo. 24465946
2014-12-20 10:45:00 TCF/Pangolin (the fly TCF) and some vertebrate TCF isoforms bind DNA through two distinct domains, a High Mobility Group (HMG) domain and a C-clamp, which recognize DNA motifs known as HMG and Helper sites, respectively. 24516405

名称对应

Type IDs
Synonymous CG17964, CG32005, CG34403, DTCF, DTcf, Dm Pan, Dmel\CG34403, Dmel_CG17964, Dmel_CG32005, IA5, LEF, LEF-1, LEF/TCF, LEF/TCF-1, LEF1, LEF1/TCF, Lef, Lef1, PAN, Pan, TCF, TCF/LEF, TCF/LEF1, TCF/Pan, Tcf, Tcf-1, Tcf/LEF, d-TCF, dTCF, dTcf, l(4)102ABb, l(4)13, lef1, pan.dTCF, tcf
Gene
UniProtKB-ID: PANG2_DROME, PANG1_DROME, H9XVM0_DROME
UniprotKB: Q8IMA8, P91943, H9XVM0
UniParc: UPI00015CFDC4, UPI00000077A7, UPI0002A81415, UPI00004ECE95, UPI00004EA837, UPI000237F707
EMBL: AY312729, BT021431, AY312732, AY312742, AY312746, AY312748, AY312738, U88538, AE014135, AY312752, AY312739, AY312734, AY312745, AY312741, AY312733, AY312744, AY312730, AY312731, AY312740, AY312737, AY312736, AY312743, BT044547, AY312750, AY312735, Y09125, BT053747, AY312747, AY312751, AY312749, BT029282
EnsemblGenome: FBgn0085432
KO: dme:Dmel_CG34403
Nucleutide sequences
EMBL-CDS: AAQ67543.1, AAQ67558.1, AAQ67544.1, AAQ67564.1, AAQ67551.1, AAQ67563.1, AAQ67546.1, AAQ67552.1, AAQ67555.1, AAQ67545.1, AAQ67556.1, AAQ67548.1, AAQ67559.1, AAQ67562.1, AAQ67550.1, AAQ67553.1, AAQ67554.1, AAQ67557.1, AAQ67560.1, AAQ67547.1, AAQ67566.1, AAQ67549.1, AAQ67561.1, ABK30919.1, AAN06549.2, AAQ67565.1, AAQ67554.1, AAQ67562.1, AAQ67559.1, AAQ67553.1, AAQ67550.1, AAQ67548.1, AAQ67556.1, AAF59371.2, CAA70343.1, AAQ67551.1, AAQ67563.1, AAN06548.2, AAQ67545.1, AAQ67546.1, AAQ67552.1, AAQ67555.1, AFH06766.1, AAN06545.1, AAC47464.1, AAQ67544.1, AAQ67564.1, AAQ67543.1, AAQ67558.1, AAQ67565.1, AAX33579.1, AAQ67561.1, ABK30919.1, AAQ67549.1, AAX52517.1, AAQ67547.1, AAQ67566.1, AAQ67560.1, ABC65830.1, ACK77665.1, AAQ67557.1, ACI03583.1, AFH06765.1
Gene_ORFName: CG34403, CG34403, CG34403, Dmel_CG34403
EnsemblGenome_TRS: FBtr0112657, FBtr0089159, FBtr0100245, FBtr0309803, FBtr0089162, FBtr0089161, FBtr0334301, FBtr0100246, FBtr0308615
Protein sequencees
EnsemblGenome_PRO: FBpp0111569, FBpp0099632, FBpp0088226, FBpp0088228, FBpp0301556, FBpp0306416, FBpp0099631, FBpp0088229, FBpp0300839
RefSeq: NP_001245406.1, NP_726528.2, NP_726527.2, NP_001245405.1, NP_524619.3, NP_001033798.1, NP_001014685.1, NP_726524.1, NP_726522.1
Others
UniRef100: UniRef100_H9XVM0, UniRef100_P91943, UniRef100_Q8IMA8
UniRef90: UniRef90_Q8IMA8, UniRef90_P91943, UniRef90_P91943-5
UniRef50: UniRef50_Q8IMA8, UniRef50_P91943-5, UniRef50_P91943
UniGene: Dm.17803

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