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43766 PlexB

43766

PlexB

Plexin B

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Plexin B

研究结论

Date Results Publications
2020-04-11 10:52:00 Secreted semaphorin 2b (Sema-2b) acts through its transmembrane receptor Plexin B (PlexB) to locally attract neural processes to specific fan-shaped body (FB) laminae. Aberrant Sema-2b/PlexB signaling leads to select disruptions in neural lamination, and these disruptions result in the formation of ectopic inhibitory connections between subsets of FB neurons. 31564592
2020-02-22 12:34:00 extracellular PlexB cleavage serves as a regulatory mechanism of PlexB signaling. Thus, the divergent roles of PlexB motifs in distinct steps of neural development contribute to its functional versatility in neural circuit assembly. 31225795
2019-01-26 12:09:00 PlexB plays a multifaceted role in instructing the assembly of the Drosophila olfactory circuit through temporally-regulated expression patterns and expression level-dependent effects. 30136927
2018-03-03 11:56:00 semaphorin 2b is a target-derived signal that acts upon presynaptic plexin B receptors to mediate the retrograde, homeostatic control of presynaptic neurotransmitter release at the neuromuscular junction in Drosophila; Sema2b-PlexB signalling regulates presynaptic homeostatic plasticity through the cytoplasmic protein Mical and the oxoreductase-dependent control of presynaptic actin 28953869
2017-04-01 11:08:00 This study demonstrated that the evidence that PlexB mediates not only Sema-2a/2b-dependent guidance functions, but also Sema-2a/2b-independent target recognition in establishing the segmental nerve a motor axon pathway. 27637927

名称对应

Type IDs
Synonymous CG17245, Dmel\CG17245, PLEXB, Plex B, plex, plex B, plexB
Gene
UniProtKB-ID: PLXB_DROME, H9XVL5_DROME
UniprotKB: Q9V4A7, H9XVL5
UniParc: UPI0000082F5C
EMBL: BT010009, AF106933, AE014135
EnsemblGenome: FBgn0025740
KO: dme:Dmel_CG17245
Nucleutide sequences
EMBL-CDS: AAF59374.2, AAD09426.1, AAQ22478.1, AFH06760.1
Gene_ORFName: CG17245, CG17245, Dmel_CG17245
EnsemblGenome_TRS: FBtr0089179, FBtr0308297, FBtr0089179, FBtr0308297
Protein sequencees
EnsemblGenome_PRO: FBpp0300616, FBpp0088246, FBpp0088246, FBpp0300616
RefSeq: NP_524616.2, NP_001245400.1
Others
UniRef100: UniRef100_Q9V4A7
UniRef90: UniRef90_Q9V4A7
UniRef50: UniRef50_Q9V4A7
UniGene: Dm.1700

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