| Type | Description |
|---|---|
| Definition | Plexin B |
| Date | Results | Publications |
|---|---|---|
| 2020-04-11 10:52:00 | Secreted semaphorin 2b (Sema-2b) acts through its transmembrane receptor Plexin B (PlexB) to locally attract neural processes to specific fan-shaped body (FB) laminae. Aberrant Sema-2b/PlexB signaling leads to select disruptions in neural lamination, and these disruptions result in the formation of ectopic inhibitory connections between subsets of FB neurons. | 31564592 |
| 2020-02-22 12:34:00 | extracellular PlexB cleavage serves as a regulatory mechanism of PlexB signaling. Thus, the divergent roles of PlexB motifs in distinct steps of neural development contribute to its functional versatility in neural circuit assembly. | 31225795 |
| 2019-01-26 12:09:00 | PlexB plays a multifaceted role in instructing the assembly of the Drosophila olfactory circuit through temporally-regulated expression patterns and expression level-dependent effects. | 30136927 |
| 2018-03-03 11:56:00 | semaphorin 2b is a target-derived signal that acts upon presynaptic plexin B receptors to mediate the retrograde, homeostatic control of presynaptic neurotransmitter release at the neuromuscular junction in Drosophila; Sema2b-PlexB signalling regulates presynaptic homeostatic plasticity through the cytoplasmic protein Mical and the oxoreductase-dependent control of presynaptic actin | 28953869 |
| 2017-04-01 11:08:00 | This study demonstrated that the evidence that PlexB mediates not only Sema-2a/2b-dependent guidance functions, but also Sema-2a/2b-independent target recognition in establishing the segmental nerve a motor axon pathway. | 27637927 |
| Type | IDs |
|---|---|
| Synonymous | CG17245, Dmel\CG17245, PLEXB, Plex B, plex, plex B, plexB |
| Gene |
UniProtKB-ID:
PLXB_DROME,
H9XVL5_DROME
UniprotKB:
Q9V4A7,
H9XVL5
UniParc:
UPI0000082F5C
EMBL:
BT010009,
AF106933,
AE014135
EnsemblGenome:
FBgn0025740
KO:
dme:Dmel_CG17245
|
| Nucleutide sequences |
EMBL-CDS:
AAF59374.2,
AAD09426.1,
AAQ22478.1,
AFH06760.1
Gene_ORFName:
CG17245,
CG17245,
Dmel_CG17245
EnsemblGenome_TRS:
FBtr0089179,
FBtr0308297,
FBtr0089179,
FBtr0308297
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0300616,
FBpp0088246,
FBpp0088246,
FBpp0300616
RefSeq:
NP_524616.2,
NP_001245400.1
|
| Others |
UniRef100:
UniRef100_Q9V4A7
UniRef90:
UniRef90_Q9V4A7
UniRef50:
UniRef50_Q9V4A7
UniGene:
Dm.1700
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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