| Type | Description |
|---|---|
| Definition | CIN85 and CD2AP related |
| Date | Results | Publications |
|---|---|---|
| 2017-12-02 12:15:00 | a genetic modifier screen that identified E3 ligases that modified the rough-eye phenotype generated by expression of cindr RNA interference transgenes during Drosophila eye development. | 29117266 |
| 2017-05-07 01:34:00 | Silencing Cindr in nephrocytes led to dramatic nephrocyte functional impairment and shortened life span, as well as collapse of nephrocyte lacunar channels and effacement of nephrocyte slit diaphragms. These phenotypes could be rescued by expression of a wild-type human CD2AP gene, but not a mutant allele derived from a patient with CD2AP-associated NS. | 28164240 |
| 2016-07-02 10:55:00 | correct Cindr-dJNK stoichiometry is essential to maintain epithelial integrity and disturbing this balance may contribute to the pathogenesis of disease states, including cancer | 26772997 |
| 2013-06-15 11:31:00 | Cindr co-localizes with Anillin at mitotic and meiotic ring canals and is recruited to the contractile ring by Anillin during male germ cell meiotic cytokinesis. | 23499247 |
| 2013-05-04 11:21:00 | Cindr recapitulates both proposed functions of its mammalian orthologs Cd2ap and Cin85: targeting the IgCAMs Rst and Hbs for endocytosis and stabilizing these heterophilic IgCAM complexes. | 23027549 |
| Type | IDs |
|---|---|
| Synonymous | BcDNA:GH03163, CD2AP, CG11316, CG1408, CG31012, Cindr, Dmel\CG31012 |
| Gene |
UniProtKB-ID:
Q9Y154_DROME,
A0A0B4KHJ8_DROME,
A0A0B4KI34_DROME,
Q86PF3_DROME,
Q9VA36_DROME,
Q9VA35_DROME,
A0A0B4KHG1_DROME,
A0A0B4KI32_DROME
UniprotKB:
Q9Y154,
A0A0B4KHJ8,
A0A0B4KI34,
Q86PF3,
Q9VA36,
Q9VA35,
A0A0B4KHG1,
A0A0B4KI32
UniParc:
UPI00029451DF,
UPI0000080D48,
UPI000007AAD2,
UPI000293EA7F,
UPI0000007667,
UPI0000007666,
UPI0002944FF6,
UPI0002942BFB
EMBL:
AF145614,
AE014297
EnsemblGenome:
FBgn0027598
KO:
dme:Dmel_CG31012
|
| Nucleutide sequences |
EMBL-CDS:
AGB96507.1,
AAF57089.1,
AAD38589.1,
AGB96506.1,
AGB96504.1,
AGB96508.1,
AAN14260.2,
AAF57087.2,
AAF57088.1,
AGB96505.1,
AGB96503.1
Gene_ORFName:
Dmel_CG31012,
CG31012,
Dmel_CG31012,
CG31012,
Dmel_CG31012,
CG31012,
Dmel_CG31012,
CG31012,
Dmel_CG31012,
CG31012,
CG31012,
Dmel_CG31012,
Dmel_CG31012,
CG31012,
Dmel_CG31012,
CG31012
EnsemblGenome_TRS:
FBtr0085706,
FBtr0310072,
FBtr0310071,
FBtr0310069,
FBtr0310424,
FBtr0085705,
FBtr0085704,
FBtr0085707,
FBtr0310070,
FBtr0310068
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0301773,
FBpp0085068,
FBpp0301772,
FBpp0301770,
FBpp0302572,
FBpp0085067,
FBpp0085066,
FBpp0085069,
FBpp0301771,
FBpp0301769
RefSeq:
NP_733406.1,
NP_001263124.1,
NP_733405.2,
NP_001263127.1,
NP_733407.2,
NP_651827.1,
NP_001263129.1,
NP_001263125.1,
NP_001263128.1,
NP_001263126.1
|
| Others |
UniRef100:
UniRef100_A0A0B4KHJ8,
UniRef100_A0A0B4KI34,
UniRef100_Q9VA35,
UniRef100_Q9VA36
UniRef90:
UniRef90_Q9VA35,
UniRef90_A0A0B4KHJ8,
UniRef90_A0A0B4KI34
UniRef50:
UniRef50_A0A0B4KHJ8,
UniRef50_A0A0B4KI34,
UniRef50_Q9VA35
UniGene:
Dm.3169
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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