| Type | Description |
|---|---|
| Definition | MRE11 homolog, double strand break repair nuclease |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:15:00 | Poly-ADP-ribosylation drives loss of protein homeostasis in ATM and Mre11 deficiency. | 33571423 |
| 2021-03-13 13:19:00 | The MRE11 complex: A versatile toolkit for the repair of broken DNA. | 32480356 |
| 2020-12-05 13:04:00 | Decreased expression of MRE11 and RAD50 in testes from humans with spermatogenic failure. | 31983050 |
| 2020-11-28 13:12:00 | Unscheduled MRE11 activity triggers cell death but not chromosome instability in polymerase eta-depleted cells subjected to UV irradiation. | 32203168 |
| 2020-10-31 13:20:00 | PCAF-Mediated Histone Acetylation Promotes Degradation by MRE11 and EXO1 in BRCA-Deficient Cells. | 32966758 |
| Type | IDs |
|---|---|
| Synonymous | ATLD, HNGS1, MRE11A, MRE11B |
| Gene |
UniProtKB-ID:
MRE11_HUMAN,
A0A024R395_HUMAN,
Q05D78_HUMAN,
F8W7U8_HUMAN
UniprotKB:
P49959,
A0A024R395,
Q05D78,
F8W7U8
UniParc:
UPI00001FA1E4,
UPI000002AE4B,
UPI000013D3FD,
UPI0000D49714,
UPI000012F4D3
EMBL:
AF303391,
AK095388,
AY584241,
AF303387,
BC063458,
AF303394,
CH471065,
AF303388,
AF303386,
AF303393,
AP000786,
KF455448,
AF022778,
AF303390,
AF303380,
AF303392,
BC017823,
AF303381,
AF303395,
AP000765,
AF303382,
AF303383,
AF303385,
AF303379,
AF303389,
AF303384,
AF073362,
U37359
Ensembl:
ENSG00000020922
KO:
hsa:4361
|
| Nucleutide sequences |
EMBL-CDS:
AAS79320.1,
AAC78721.1,
BAG53039.1,
AAH63458.1,
AAC36249.1,
AAD10197.1,
AAK18790.1,
EAW66933.1,
EAW66930.1,
EAW66932.1,
AAH17823.1
Gene_ORFName:
hCG_2032472
Ensembl_TRS:
ENST00000407439,
ENST00000323977,
ENST00000323929,
ENST00000393241
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000385614,
ENSP00000326094,
ENSP00000325863,
ENSP00000376933
RefSeq:
XP_016873261.1,
NP_005582.1,
NP_001317276.1,
XP_005274065.1,
NP_005581.2,
XP_011541139.1,
XP_006718905.1
|
| Others |
UniRef100:
UniRef100_P49959,
UniRef100_F8W7U8,
UniRef100_Q05D78
UniRef90:
UniRef90_Q05D78,
UniRef90_Q60HE6,
UniRef90_P49959
UniRef50:
UniRef50_A0A674BE63,
UniRef50_P49959
UniGene:
Hs.192649
CCDS:
CCDS8299.1,
CCDS8298.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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