| Type | Description |
|---|---|
| Definition | similar |
| Date | Results | Publications |
|---|---|---|
| 2020-01-11 10:45:00 | In the mutant for Trh smaller synaptic boutons form clusters named satellite boutons appear at larval neuromuscular junctions, which is induced by the reduction of internal oxygen levels due to defective tracheal branches. Sima is critical in mediating hypoxia-induced satellite bouton formation. Sima upregulates the level of the Wg signal in glia, leading to reorganized microtubule structures within presynaptic sites. | 31381576 |
| 2017-11-25 13:15:00 | most HIF1A targets require either TIP60, the CDK8-Mediator complex, or both as coactivators for full expression in hypoxia. | 27320910 |
| 2017-06-10 11:41:00 | Musashi is a novel regulator of HIF that inhibits responses to hypoxia specifically when oxygen is available. | 27141964 |
| 2017-05-27 10:52:00 | miR-190 is a novel regulator of the hypoxia response that represses the oxygen sensor Fatiga, leading to HIFalpha stabilization and enhancement of hypoxic responses. | 27223464 |
| 2015-10-03 10:04:00 | These results indicate that HIF-1alpha is required to restrain the NF-kappaB response, and thus prevents excessive and damaging pro-inflammatory responses. | 25510503 |
| Type | IDs |
|---|---|
| Synonymous | 7951, CG31031, CG45051, CG7951, DMU43090, Dmel\CG45051, Dmel_CG31031, Dmel_CG7951, HIF alpha, HIF-1, HIF-1alpha, HIF-alpha/sima, HIF1A, HIF1alpha, HIFalpha, Hif-1A, Hif1alpha, SIMA, Sima, bHLHe56, dHIF-1alpha, dHIF-alpha, l(3)j11B7 |
| Gene |
UniProtKB-ID:
SIMA_DROME,
A0A0B4KHI3_DROME,
B7Z0S3_DROME,
A0A0B4LIX2_DROME
UniprotKB:
Q24167,
A0A0B4KHI3,
B7Z0S3,
A0A0B4LIX2
UniParc:
UPI00016DF807,
UPI0002ADBC92,
UPI0003954CE1,
UPI000012493D
EMBL:
AE014297,
U43090
EnsemblGenome:
FBgn0266411
KO:
dme:Dmel_CG45051
|
| Nucleutide sequences |
EMBL-CDS:
AAC47303.1,
AAF57008.2,
AGB96479.1,
ACL83585.1,
AHN57598.1
Gene_ORFName:
CG45051,
Dmel_CG45051,
CG45051,
CG45051,
Dmel_CG45051,
Dmel_CG45051,
CG45051
EnsemblGenome_TRS:
FBtr0344374,
FBtr0344373,
FBtr0344375,
FBtr0344376
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0310747,
FBpp0310746,
FBpp0310748,
FBpp0310749
RefSeq:
NP_001263100.1,
NP_001287599.1,
NP_001138129.1,
NP_524584.2
|
| Others |
UniRef100:
UniRef100_Q24167,
UniRef100_B7Z0S3,
UniRef100_A0A0B4LIX2
UniRef90:
UniRef90_Q24167,
UniRef90_B7Z0S3
UniRef50:
UniRef50_B7Z0S3,
UniRef50_Q24167
UniGene:
Dm.6953
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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