| Type | Description |
|---|---|
| Definition | N-methylpurine DNA glycosylase |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 14:02:00 | Recognition of 1,N (2)-ethenoguanine by alkyladenine DNA glycosylase is restricted by a conserved active-site residue. | 31882538 |
| 2020-03-14 11:37:00 | AAG binds to chromatin and forms complex with RNA polymerase (pol) II. This occurs through direct interaction with Elongator and results in transcriptional co-regulation. | 31784530 |
| 2019-06-29 11:31:00 | Although AAG strongly prefers to excise lesions from duplex DNA, nonspecific binding is comparable for single- and double-stranded nonspecific sites. The electrostatically driven binding of AAG to small DNA sites ( approximately 5 nucleotides of single-stranded and approximately 6 base pairs of duplex) facilitates the search for DNA damage in chromosomal DNA, which is bound by nucleosomes and other proteins. | 29940097 |
| 2019-03-02 11:50:00 | PIG11 may act as a candidate liver tumor suppressor. | 30241046 |
| 2017-11-04 12:41:00 | high levels of APNG were associated with better overall survival in patients with glioblastoma | 28662073 |
| Type | IDs |
|---|---|
| Synonymous | AAG, ADPG, APNG, CRA36.1, MDG, Mid1, PIG11, PIG16, anpg |
| Gene |
UniProtKB-ID:
3MG_HUMAN,
Q1W6H1_HUMAN
UniprotKB:
P29372,
Q1W6H1
UniParc:
UPI0000169F5F,
UPI00001FF954,
UPI000002A2C0,
UPI000002A2BF
EMBL:
BC014991,
AY258284,
X56528,
DQ431198,
L10752,
CH471112,
Z69720,
M74905,
M99626,
AE006462,
AY305873,
S51033,
M71215,
AF499437
Ensembl:
ENSG00000103152
KO:
hsa:4350
|
| Nucleutide sequences |
EMBL-CDS:
CAA93540.1,
AAB19537.1,
AAF77073.1,
AAM14628.1,
AAK61213.1,
AAB46421.1,
CAI95610.1,
AAA58369.1,
AAP82229.1,
CAA39875.1,
AAQ95215.1,
AAH14991.1,
EAW85871.1,
AAA58627.1,
ABD95906.1,
EAW85872.1
Gene_ORFName:
hCG_22412
Ensembl_TRS:
ENST00000219431,
ENST00000356432,
ENST00000397817
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000219431,
ENSP00000380918,
ENSP00000348809
RefSeq:
NP_001015052.1,
NP_002425.2,
NP_001015054.1,
XP_024306050.1
|
| Others |
UniRef100:
UniRef100_P29372
UniRef90:
UniRef90_P29372
UniRef50:
UniRef50_P29372
UniGene:
Hs.459596
CCDS:
CCDS42087.1,
CCDS32345.1,
CCDS32346.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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