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434215 Lrrc32

434215

Lrrc32

leucine rich repeat containing 32

protein-coding

Mus musculus

基因描述

Type Description
Definition leucine rich repeat containing 32

研究结论

Date Results Publications
2021-01-30 13:02:00 Thrombin contributes to cancer immune evasion via proteolysis of platelet-bound to activate LTGF-beta. 31915300
2019-11-30 12:28:00 Study demonstrated that B cells are required for the induction of oral tolerance of T cell-dependent antigens via and revealed for the first time that cell surface is an important checkpoint for regulating B cell peripheral tolerance, highlighting a mechanism of autoimmune disease pathogenesis. 29618665
2017-11-25 14:10:00 Data (including data from studies using knockout mice) suggest that Garp/Lrrc32 is involved in up-regulation of Tgfb3 and is essential for normal embryogenesis of palate; knockout of Garp causes postnatal lethality, cleft palate, and decreased apoptosis and Smad2 phosphorylation in medial edge epithelial cells of palatal shelf of embryos. (Tgfb3 = transforming growth factor beta 3; Smad2 = MAD homolog protein 2) 28912269
2015-12-19 10:08:00 These results demonstrate the unexpected presence of on Hepatic stellate cells and its significance in regard to the ability of Hepatic stellate cells to activate latent TGF-beta1 and thereby inhibit T cells. 26246140
2015-09-26 13:14:00 expression on MSCs contributed to their ability to inhibit T-cell responses in vitro. 25182959

名称对应

Type IDs
Synonymous AI426318, D11S833Eh, D7H11S833E, EG434215, Garp
Gene
UniProtKB-ID: LRC32_MOUSE
UniprotKB: G3XA59
UniParc: UPI00000235C5
EMBL: AC115069, CH466531
Ensembl: ENSMUSG00000090958
KO: mmu:434215
Nucleutide sequences
EMBL-CDS: EDL16346.1
Ensembl_TRS: ENSMUST00000165205, ENSMUST00000205956
Protein sequencees
Ensembl_PRO: ENSMUSP00000133205, ENSMUSP00000145859
RefSeq: XP_006508041.1, XP_006508042.1, NP_001106850.1
Others
UniRef100: UniRef100_G3XA59
UniRef90: UniRef90_G3XA59
UniRef50: UniRef50_Q14392
UniGene: Mm.323057
CCDS: CCDS52319.1

全选

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