| Type | Description |
|---|---|
| Definition | meningioma 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-09-01 10:22:00 | identified Meis2 as critical to MN1-induced leukemia, with essential roles in proliferation, self-renewal, impairment of differentiation and disease progression in vitro and in vivo. | 28960191 |
| 2016-08-20 10:40:00 | MLL1 and DOT1L cooperate with meningioma-1 to induce acute myeloid leukemia. | 26927674 |
| 2013-11-30 12:02:00 | The critical amino acid residues in the murine MN1 protein necessary for the neoplastic myeloid transformation have been identified. | 23626719 |
| 2013-02-16 11:34:00 | Overexpression of MN1 confers resistance to chemotherapy, accelerates leukemia onset, and suppresses p53 and Bim induction | 22905229 |
| 2010-05-03 12:09:00 | Data show that genetic disruption of both FLT3 and c-Kit signaling in the MN1-leukemia model was dispensable for MN1-induced leukemogenesis. | 20096329 |
| Type | IDs |
|---|---|
| Synonymous | AA003644, AA009236 |
| Gene |
UniProtKB-ID:
MN1_MOUSE
UniprotKB:
D3YWE6
UniParc:
UPI00006050BC
EMBL:
AC124749,
AC122226
Ensembl:
ENSMUSG00000070576
KO:
mmu:433938
|
| Nucleutide sequences |
Ensembl_TRS:
ENSMUST00000094463
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000092034
RefSeq:
NP_001074704.1
|
| Others |
UniRef100:
UniRef100_D3YWE6
UniRef90:
UniRef90_D3YWE6
UniRef50:
UniRef50_Q10571
UniGene:
Mm.332576
CCDS:
CCDS39214.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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