| Type | Description |
|---|---|
| Definition | tripartite motif-containing 63 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-19 13:43:00 | Identification and characterization of Fbxl22, a novel skeletal muscle atrophy-promoting E3 ubiquitin ligase. | 32783651 |
| 2019-05-25 11:59:00 | The study reveals mechanisms by which MuRF1 may transcriptionally regulate anti-oxidant systems in the face of chronic hypoxia leading to right heart failure. | 30241514 |
| 2018-09-08 12:02:00 | Oligonol-mediated downregulation of Atrogin-1 and MuRF1 gene expression alleviates muscle loss and improves the impaired myotube formation, indicating that oligonol supplementation may be useful for the attenuation of myotube loss. | 28930190 |
| 2018-06-30 10:29:00 | the present study indicates that excessive glucocorticoids increased ubiquitin-proteasome system -dependent protein proteolysis via stimulating MuRF1, but not atrogin-1. | 29046370 |
| 2017-06-24 12:19:00 | Dexamethasone-induced MuRF1 upregulation was significantly attenuated in C2C12 myotubes by resveratrol in vitro, but this effect on C2C12 myotubes was abrogated by a knockdown of NF-kappaB, suggesting that the beneficial effect of resveratrol was NF-kappaB dependent. Our findings provide novel information about the ability of resveratrol to prevent or treat muscle atrophy induced by CKD. | 28392400 |
| Type | IDs |
|---|---|
| Synonymous | MuRF1, RF1, Rnf28 |
| Gene |
UniProtKB-ID:
F8VPZ1_MOUSE,
Q8CFN7_MOUSE
UniprotKB:
F8VPZ1,
Q8CFN7
UniParc:
UPI00000E8FA5,
UPI0000EF892F
EMBL:
AJ278734,
AL627314,
AL627253
Ensembl:
ENSMUSG00000028834
KO:
mmu:433766
|
| Nucleutide sequences |
EMBL-CDS:
CAC82103.1
Ensembl_TRS:
ENSMUST00000105875
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000101501
RefSeq:
NP_001356174.1,
NP_001034137.2
|
| Others |
UniRef100:
UniRef100_F8VPZ1
UniRef90:
UniRef90_Q969Q1
UniRef50:
UniRef50_Q969Q1
UniGene:
Mm.331961
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员