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4331 MNAT1

4331

MNAT1

MNAT1 component of CDK activating kinase

protein-coding

Homo sapiens

基因描述

Type Description
Definition MNAT1 component of CDK activating kinase

研究结论

Date Results Publications
2021-03-27 14:42:00 The regulatory effect of has-circ-0001146/miR-26a-5p/MNAT1 network on the proliferation and invasion of osteosarcoma. 32453410
2020-08-01 15:16:00 Study presents the high-resolution crystal structure of the Arch domain of XPD with its interaction partner MAT1, a central component of the CDK activating kinase complex. The analysis of the interface led to the identification of amino acid residues that are crucial for the MAT1-XPD interaction. 32245994
2019-09-21 12:22:00 MAT1 serves as a promoter in the lung metastasis of osteosarcoma through increasing AKT1 expression. 31421084
2019-02-02 10:46:00 MNAT1 binds to p53, mediates p53 ubiquitin-degradation through MDM2, increases cell growth and decreases cell apoptosis, and finally promotes CRC malignance. 30477538
2018-01-20 10:53:00 Expressions of components of the CAK complex, CDK7, MAT1, and Cyclin H are elevated in breast cancer. 27301701

名称对应

Type IDs
Synonymous CAP35, MAT1, RNF66, TFB3
Gene
UniProtKB-ID: MAT1_HUMAN, A0A024R669_HUMAN, A0A024R688_HUMAN
UniprotKB: P51948, A0A024R669, A0A024R688
UniParc: UPI000002FC14, UPI0000D9BC5A
EMBL: AL132777, X87843, U61835, X92669, KU178191, AY165512, CH471061, AL160236, CR450336, BC000820
Ensembl: ENSG00000020426
KO: hsa:4331
Nucleutide sequences
EMBL-CDS: EAW80787.1, AAB05248.1, AAN47195.1, EAW80788.1, CAA63356.1, AAH00820.1, CAA61112.1, CAG29332.1, EAW80791.1, EAW80789.1, ALQ33649.1
Gene_ORFName: hCG_21923, hCG_21923
Ensembl_TRS: ENST00000261245, ENST00000539616
Protein sequencees
Ensembl_PRO: ENSP00000446437, ENSP00000261245
RefSeq: XP_016876822.1, XP_016876821.1, XP_016876823.1, XP_005267744.1, XP_024305367.1, XP_005267745.1, NP_001171434.1, NP_002422.1
Others
UniRef100: UniRef100_P51948, UniRef100_A0A024R669
UniRef90: UniRef90_P51948
UniRef50: UniRef50_P51948
UniGene: Hs.509523
CCDS: CCDS53899.1, CCDS9750.1

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