| Type | Description |
|---|---|
| Definition | adenylate cyclase 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-07-06 11:22:00 | results show that adenylyl cyclase 1 is a major isoform for apoA-1-activated cAMP signaling to promote cholesterol transport and exocytosis to the surface of THP-1 macrophage foam cells | 29444935 |
| 2018-12-01 12:11:00 | Data show in fragile X mental retardation syndrome 1 protein (Fmr1) knockout neurons, type 1 adenylyl cyclase (Adcy1) mRNA translation is enhanced, leading to excessive production of ADCY1 protein and insensitivity to neuronal stimulation. | 28218269 |
| 2017-11-25 15:28:00 | data indicate that ST034307 is a selective small-molecule inhibitor of AC1 and suggest that selective AC1 inhibitors may be useful for managing pain. | 28223412 |
| 2017-11-11 10:40:00 | Genetic deletion of AC8 (adenylyl cyclase 8) but not AC1 abolished long-lasting anxiety. | 27234425 |
| 2016-12-17 12:02:00 | Following ethanol administration, phosphorylation of TrkB is significantly increased in the striatum of Adcyl1 and Adcyl6 knock-out mice. | 26992697 |
| Type | IDs |
|---|---|
| Synonymous | AC1, D11Bwg1392e, I-AC, brl |
| Gene |
UniProtKB-ID:
ADCY1_MOUSE
UniprotKB:
O88444
UniParc:
UPI0000470555
EMBL:
AL669838,
AF053980
Ensembl:
ENSMUSG00000020431
KO:
mmu:432530
|
| Nucleutide sequences |
EMBL-CDS:
AAC29478.1
Ensembl_TRS:
ENSMUST00000020706
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000020706
RefSeq:
NP_033752.1
|
| Others |
UniRef100:
UniRef100_O88444
UniRef90:
UniRef90_O88444
UniRef50:
UniRef50_O88444
UniGene:
Mm.259733
CCDS:
CCDS24426.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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