Akap7 - A kinase (PRKA) anchor protein 7-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

收藏

432442 Akap7

基因描述

Type	Description
Definition	A kinase (PRKA) anchor protein 7

研究结论

Date	Results	Publications
2017-11-04 12:49:00	Genetic ablation of AKAP7 specifically from dentate granule cells results in disruption of mossy fiber-CA3 pyramidal neuron long-term potentiation directly initiated by cAMP, and the AKAP7 mutant mice are selectively deficient in pattern separation behaviors. The results suggest that the complex in the mossy fiber projections plays an essential role in synaptic plasticity and contextual memory formation.	27911261
2015-07-25 10:08:00	The results demonstrate that green tea catechins enhance lipolysis in the presence of norepinephrine via a pathway in 3T3-L1 adipocytes, providing a potential mechanism by which green tea catechins could reduce body fat.	25849890
2014-03-01 13:00:00	Protein kinase A activation enhances hippocampal mossy fiber glutamatergic transmission.	24381273
2013-01-05 10:55:00	AKAP7 is not required for regulation of Ca(2+) handling in mouse cardiomyocytes.	23035250
2011-07-23 11:33:00	AKAP15 co-immunoprecipitates with CaV1.2 and CaV1.3 channels. AKAP15 has overlapping localization with CaV1.2 and CaV1.3 channels in cell bodies and proximal dendrites and is closely co-localized with CaV1.2 channels in punctate clusters.	21224388

名称对应

Type	IDs
Synonymous	6430401D08, AI662165, AKAP15, Akap18, BB170514
Gene	UniProtKB-ID: AKA7G_MOUSE, AKA7A_MOUSE UniprotKB: Q7TN79, O55074 UniParc: UPI0000D6332E, UPI00001E4AED EMBL: CH466540, AF047716, AC153550, AY301068, AC153549 Ensembl: ENSMUSG00000039166 KO: mmu:432442
Nucleutide sequences	EMBL-CDS: AAP55205.1, EDL04795.1, AAC40085.1 Ensembl_TRS: ENSMUST00000041984, ENSMUST00000100012
Protein sequencees	Ensembl_PRO: ENSMUSP00000043624, ENSMUSP00000097590 RefSeq: NP_001366168.1, XP_036011779.1, XP_006512854.1, XP_006512856.1, NP_001366167.1, XP_006512857.1, XP_006512852.1, XP_006512853.1, XP_036011780.1, XP_017169512.1, XP_030101017.1, NP_061217.3, NP_001334389.1, XP_030101016.1, NP_001366169.1, XP_006512851.1
Others	UniRef100: UniRef100_Q7TN79, UniRef100_O55074 UniRef90: UniRef90_O55074, UniRef90_Q6JP77 UniRef50: UniRef50_Q6JP77, UniRef50_O55074 UniGene: Mm.485937, Mm.487103 CCDS: CCDS23753.1, CCDS83688.1

全选

{{proteinIndex+1}}

mRNA

Protein

UniprotKB

Description

Refseq

{{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}

Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location

( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

收藏到我的文献

全选

Pubmed编号	文献信息	发表日期	相关基因
27911261	Targeted deletion of AKAP7 in dentate granule cells impairs spatial discrimination. Elife Brian W Jones , Jennifer Deem , Thomas J Younts , Michael Weisenhaus , Christina A Sanford , Margaret C Slack , Jenesa Chin , Daniela Nachmanson , Alex McKennon , Pablo E Castillo , G Stanley McKnight	2016-12-02	-
25849890	Green tea catechins enhance norepinephrine-induced lipolysis via a protein kinase A-dependent pathway in adipocytes. Biochem. Biophys. Res. Commun. Shu Chen , Noriko Osaki , Akira Shimotoyodome	2015-05-22	Akap7
24381273	Presynaptic Î±7 nicotinic acetylcholine receptors enhance hippocampal mossy fiber glutamatergic transmission via PKA activation. J. Neurosci. Qing Cheng , Jerrel L Yakel	2014-01-01	Chrna7, Akap7
23035250	Cardiomyocytes from AKAP7 knockout mice respond normally to adrenergic stimulation. Proc. Natl. Acad. Sci. U.S.A. Brian W Jones , Sylvain Brunet , Merle L Gilbert , C Blake Nichols , Thomas Su , Ruth E Westenbroek , John D Scott , William A Catterall , G Stanley McKnight	2012-10-16	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
21224388	Functional roles of a C-terminal signaling complex of CaV1 channels and A-kinase anchoring protein 15 in brain neurons. J Biol Chem Misty R Marshall , John Patrick Clark , Ruth Westenbroek , Frank H Yu , Todd Scheuer , William A Catterall	2011-04-08	-
21216955	Deletion of the distal C terminus of CaV1.2 channels leads to loss of beta-adrenergic regulation and heart failure in vivo. J Biol Chem Ying Fu , Ruth E Westenbroek , Frank H Yu , John P Clark , Misty R Marshall , Todd Scheuer , William A Catterall	2011-04-08	-
20120617	Genetic evidence for a role for protein kinase A in the maintenance of sleep and thalamocortical oscillations. Sleep Kevin Hellman , Pepe Hernandez , Alice Park , Ted Abel	2010-01-01	-
18799693	Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. Gwenn M Hansen , Diane C Markesich , Michael B Burnett , Qichao Zhu , Karen M Dionne , Lizabeth J Richter , Richard H Finnell , Arthur T Sands , Brian P Zambrowicz , Alejandro Abuin	2008-10-01	Gm11335, Gm17762, A930017K11Rik, BC028777, Gm13999, Gm11696, Gm12359, Gm10589, D030047H15Rik, Gm10856, Gm10685, Gm10062, Gm10433, Gm10648, Gm10840, Gm15441, Gm10684, Gm9900, Gm10822, Gm10687, Gm11744, Gm10747, Arih2os, B230344G16Rik, Fmr1os, Tmem51os1, Gm14488, Gm13033, Gm10789, Gm10615, Gm1976, Gm9967, Gm9917, Gm1974, Gm11496, Gm13580, Gm2085, Gm2183, Gm2245, Tbx3os1, Gm12980, Gm2329, Lncenc1, Gm2381, Snhg12, Gm2479, Gm12942, Gm2529, Gm2533, Rpl30-ps7, Rsf1os2, Gm2695, 2810416G20Rik, Rpl30-ps6, Gm2773, Gm2788, Dynlt1f, Gm9793, Gm2885, Gm2920, Gm15506, Gm11627, Gm10518, Gm13496, Gm3134, Gm12827, Gm3143, Gm10144, Ahnak2, Gm3196, Gm13242, Gm3325, Gm13247, Gm10863, Gm13157, 4930522L14Rik, Gm3552, Gm15226, Gm3604, Gm3643, BC005561, Gm3716, 2810410L24Rik, Gm10282, Gm3839, Nhsl2, 4732419C18Rik, Gm3906, Gm3973, Gm4013, Apol7d, Gm12057, Gm10489, Rex2, 1110002L01Rik, Gm4189, Gm4204, 4632428C04Rik, 9130023H24Rik
17967808	EUCOMM--the European conditional mouse mutagenesis program. Brief Funct Genomic Proteomic Roland H Friedel , Claudia Seisenberger , Cornelia Kaloff , Wolfgang Wurst	2007-09-01	Gm11696, Gm10589, Apela, Gm10822, Gm2085, Gm2312, Lncenc1, Gm2381, Gm2659, Gm2679, Dynlt1c, Gm3134, Gm3143, Gm3236, Gm3574, Gm3581, Gm3718, Gm3859, Gm3905, Gm3952, Gm3957, Gm3973, Gm12057, Rex2, Gm4218, Gm4225, Gm16476, Gm4407, Gm14410, Gm4420, Gm14005, 1300002E11Rik, Gm4532, Srcap, Gm17789, Gm10751, Gm14321, 0610009E02Rik, Gm12758, Gm11532, Phactr4, Rusc2, AK010878, Gm10778, 5830417I10Rik, Mir1902, Gm15270, Gm11767, Ino80dos, Bsdc1, Gm7645, Gm20590, Slc44a1, Gm15545, Gm17292, 2900009J06Rik, Kifc1, Gm13150, Gm19426, Gm19428, Gm19474, Gm14963, Gm19565, Gm19592, Gm12588, Snhg4, Gm19702, Gm19705, Platr22, Nuggc, Zfp534, Gm19860, Gm11725, Gm19876, Gm19889, Gm16201, Gm13056, Tnfsf13os, Gm19925, Gm19976, Gm20014, Gm16740, Gm20039, Gm20045, AU020206, Ccdc170, Trp53cor1, Gm20266, Gm20324, Zfp518b, Gm14401, AI480526, Pds5b, Ube3c, Gm21297, Akap9, Gm29724, Itfg2, Parp11

研究热度

热点单位

排名	科研单位	文献
{{affIndex+1}}	{{aff.value}}	{{aff.size}}

目前还没有研究热点单位

热点人员

排名	研究人员	文献
{{authorIndex+1}}	{{author.value}}	{{author.size}}

目前还没有研究热点人员

© 2017 biocloud.net版权所有 ICP证：京10042835号