| Type | Description |
|---|---|
| Definition | polycystic kidney disease 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-06-15 10:55:00 | Study shows that TMEM33 interacts with the ion channel polycystin-2 at the endoplasmic reticulum (ER) membrane, enhancing its opening over the whole physiological calcium range in ER liposomes fused to planar bilayers. Results identify a key role for TMEM33 in the regulation of intracellular calcium homeostasis of renal proximal convoluted tubule cells and establish a causal link between TMEM33 and acute kidney injury. | 31048699 |
| 2017-05-27 10:46:00 | Results show that Far Upstream Element-Binding Protein 1 Binds the 3' Untranslated Region of PKD2 to inhibit PKD2 translation, regulating zebrafish disease phenotypes associated with PKD2 knockdown | 26839368 |
| 2016-04-23 11:33:00 | TRPP2 and TRPV4 are mechanosensitive channels in the endocardium.Oscillatory flow modulates mechanosensitive klf2a expression through trpv4 and trpp2 during heart valve development. | 25959969 |
| 2016-01-16 10:41:00 | Intraciliary calcium oscillations depend on Pkd2 and are left-biased at the left-right organizer in response to ciliary motility. | 25660539 |
| 2014-08-28 16:15:00 | TRPP2 utilizes TRPV4 to form a mechano- and thermosensitive molecular sensor in the cilium.[TRPP2] | 18695040 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
PKD2_DANRE
UniprotKB:
Q6IVV8
UniParc:
UPI00003786E1
EMBL:
AY618926,
CR788312,
DQ175629
Ensembl:
ENSDARG00000014098
KO:
dre:432387
|
| Nucleutide sequences |
EMBL-CDS:
AAT39122.1,
ABA60692.1
Ensembl_TRS:
ENSDART00000020412
|
| Protein sequencees |
Ensembl_PRO:
ENSDARP00000027024
RefSeq:
XP_017209279.1,
XP_009292468.1,
NP_001002310.1
|
| Others |
UniRef100:
UniRef100_Q6IVV8
UniRef90:
UniRef90_Q6IVV8
UniRef50:
UniRef50_O35245
UniGene:
Dr.92211
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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