| Type | Description |
|---|---|
| Definition | NPC1 like intracellular cholesterol transporter 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-03-25 10:54:00 | Decreased mRNA levels of HNF4alpha and SREBP2 in mice could be involved in the reduction in NPC1L1 expression. | 25716431 |
| 2015-11-21 11:05:00 | demonstrate that Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter, plays a central role in intestinal VK uptake and modulates the anticoagulant effect of warfarin. In | 25696002 |
| 2011-12-17 11:39:00 | Cdc42 controls the cholesterol-regulated transport and localization of NPC1L1, and plays a role in cholesterol absorption. | 21844200 |
| 2011-09-24 11:36:00 | The increased expression of NPC1L1 might contribute to hypercholesterolemia, which may be involved in the pathogenesis of transplant arteriosclerosis. | 21631994 |
| 2011-02-26 10:31:00 | flotillins have a role in NPC1L1-mediated cholesterol uptake and NPC1L1-flotillins-postive cholesterol-enriched membrane microdomains are involved in the mechanism for efficient cholesterol absorption | 21187433 |
| Type | IDs |
|---|---|
| Synonymous | SLC66A2 |
| Gene |
UniProtKB-ID:
NPCL1_RAT
UniprotKB:
Q6T3U3
UniParc:
UPI000023FF83
EMBL:
AY437867
Ensembl:
ENSRNOG00000049955
KO:
rno:432367
|
| Nucleutide sequences |
EMBL-CDS:
AAR97888.1
Ensembl_TRS:
ENSRNOT00000075827
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000065524
RefSeq:
NP_001002025.1
|
| Others |
UniRef100:
UniRef100_Q6T3U3
UniRef90:
UniRef90_Q6T3U3
UniRef50:
UniRef50_Q9UHC9
UniGene:
Rn.123563
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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