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4321 MMP12

4321

MMP12

matrix metallopeptidase 12

protein-coding

Homo sapiens

基因描述

Type Description
Definition matrix metallopeptidase 12

研究结论

Date Results Publications
2021-03-20 13:28:00 Matrix Metalloproteinase Genes (MMP1, MMP10, MMP12) on Chromosome 11q22 and the Risk of Non-Contact Anterior Cruciate Ligament Ruptures. 32650441
2021-01-30 13:02:00 MMP-12 as a potential biomarker to forecast ischemic stroke in obese patients. 31862687
2020-12-19 13:44:00 Revisiting matrix metalloproteinase 12: its role in pathophysiology of asthma and related pulmonary diseases. 33065600
2020-05-23 10:47:00 Results detected that MMP12 expression is increased in castration-resistant prostate cancer (CRPC) patients tissues, and its knockdown attenuates CRPC cell line invasion. Also, endogenous estrogen produced by aromatase upregulates MMP12 expression via ERalpha. These data suggest that upregulating MMP12 expression may be a crucial mechanism by which aromatase promotes CRPC metastasis. 31499120
2019-11-23 12:46:00 MMP-12 induces pro-osteogenic responses in aortic valve interstitial cells ( AVICs) by activation of p38 MAPK-mediated LRP-6 and beta-catenin signaling pathways. 30691826

名称对应

Type IDs
Synonymous HME, ME, MME, MMP-12
Gene
UniProtKB-ID: MMP12_HUMAN
UniprotKB: P39900
UniParc: UPI00000422BE
EMBL: CH471065, BC112301, AY856072, AK313959, BC143773, L23808
Ensembl: ENSG00000262406
KO: hsa:4321
Nucleutide sequences
EMBL-CDS: EAW67033.1, AAW29944.1, BAG36675.1, AAA58658.1, AAI43774.1, AAI12302.1
Ensembl_TRS: ENST00000571244
Protein sequencees
Ensembl_PRO: ENSP00000458585
RefSeq: NP_002417.2
Others
UniRef100: UniRef100_P39900
UniRef90: UniRef90_P39900
UniRef50: UniRef50_P39900
UniGene: Hs.1695, Hs.709832
CCDS: CCDS73375.1

全选

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研究热度

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