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432 ASGR1

432

ASGR1

asialoglycoprotein receptor 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition asialoglycoprotein receptor 1

研究结论

Date Results Publications
2020-10-24 13:57:00 ASGR1 but not FOXM1 expression decreases in the peripheral blood mononuclear cells of diabetic atherosclerotic patients. 31202960
2020-07-04 10:56:00 Our findings suggest that Clec10a in mice and Asgr1 in humans play an important role in skin homeostasis against inflammation associated with house dust mite-induced dermatitis. 31811054
2018-06-16 11:15:00 Authors report the generation of a human embryonic stem cell line WAe001-A-6 harbouring homozygous ASGR1 mutations using CRISPR/Cas9. The mutation involves a 37bp deletion, resulting in a frame shift. 28952928
2017-09-30 12:04:00 PEGylated lipoplexes were well tolerated by both HEK293 (ASGP-R-negative) and HepG2 (ASGP-R-positive) cell lines and delivered DNA to the hepatoma cell line HepG2 by ASGP-R mediation at levels three-fold greater than nonPEGylated lipoplexes. 28063265
2017-08-12 10:19:00 findings show that the hepatitis E virus (HEV) ORF2 protein interacts directly with the ectodomain of both ASGR1 and ASGR2; ASGPR is involved in and facilitates HEV infection by binding to ORF2 27155063

名称对应

Type IDs
Synonymous ASGPR, ASGPR1, CLEC4H1, HL-1
Gene
UniProtKB-ID: ASGR1_HUMAN, Q6FGQ5_HUMAN
UniprotKB: P07306, Q6FGQ5
UniParc: UPI0000001604, UPI0001DB84DC
EMBL: AC120057, M10058, BC032130, AB070933, CH471108, FJ410292, CR542052, BT019873
Ensembl: ENSG00000141505
KO: hsa:432
Nucleutide sequences
EMBL-CDS: AAH32130.1, AAA51785.1, BAB83508.1, ACQ90237.1, CAG46849.1, EAW90257.1, AAV38676.1, EAW90256.1, EAW90258.1
Gene_ORFName: hCG_1985284
Ensembl_TRS: ENST00000574388, ENST00000619926, ENST00000269299
Protein sequencees
Ensembl_PRO: ENSP00000481182, ENSP00000269299, ENSP00000459169
RefSeq: XP_011522163.1, NP_001662.1, NP_001184145.1
Others
UniRef100: UniRef100_P07306
UniRef90: UniRef90_P07306
UniRef50: UniRef50_P07307
UniGene: Hs.12056, Hs.731669
CCDS: CCDS56017.1, CCDS11089.1

全选

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