| Type | Description |
|---|---|
| Definition | Enhancer of split m8, helix-loop-helix |
| Date | Results | Publications |
|---|---|---|
| 2017-07-22 10:40:00 | The conserved MAPK site in E(spl)-M8, an effector of Drosophila notch signaling, controls repressor activity during eye development. | 27428327 |
| 2016-01-02 11:53:00 | Studies identify PP2A-Wdb as a participant in Notch signaling, and suggest that M8 activity is controlled by phosphorylation and dephosphorylation. | 25006677 |
| 2013-06-01 11:57:00 | Based on these data, we propose a model in which Hes genes are responsible for co-ordinating the Notch response of a wide spectrum of other targets, explaining the critical functions these key regulators play in many developmental and disease contexts. | 23300480 |
| 2013-01-05 11:28:00 | Da transactivation domains play essential roles in neurogenesis and in E(spl)-mediated repression. | 22949507 |
| 2012-05-05 10:04:00 | E(spl) and Dpn act together to maintain the neuroblasts in a self-renewing state, a process in which they are assisted by Notch, which sustains expression of the E(spl) subset | 22357926 |
| Type | IDs |
|---|---|
| Synonymous | CG8365, Dmel\CG8365, E(Spl), E(spl), E(spl) m8, E(spl)-C, E(spl)-M8, E(spl)-m8, E(spl)M8, E(spl)bHLH, E(spl)m8, En(spl), En(spl)-C, Espl, HLHm8, Hes, M8, Su(H)[[m8]], anon-EST:Liang-1.71, bHLHb36, clone 1.71, e(spl), l(3)96Fd, m8 |
| Gene |
UniProtKB-ID:
ESM8_DROME
UniprotKB:
P13098
UniParc:
UPI0000124964
EMBL:
AY779918,
BT028861,
BT028829,
AY779911,
AY779917,
AY779913,
AY779915,
AY779910,
AY779919,
AY779916,
BT028834,
AY779912,
AY779908,
DQ138662,
X16553,
BT028867,
AY779906,
AY779921,
AY779909,
AY779914,
AE014297,
AY779907,
AY779920
EnsemblGenome:
FBgn0000591
KO:
dme:Dmel_CG8365
|
| Nucleutide sequences |
EMBL-CDS:
CAA34554.1,
ABA86268.1,
AAV59135.1,
AAV59159.1,
AAV59123.1,
AAV59051.1,
AAV59111.1,
AAV59207.1,
AAF56555.1,
ABI34242.1,
AAV59219.1,
AAV59183.1,
AAV59087.1,
AAV59147.1,
ABI34210.1,
AAV59075.1,
AAV59195.1,
ABI34215.2,
AAV59063.1,
AAV59231.1,
AAV59171.1,
AAV59099.1,
ABI34248.2
Gene_ORFName:
CG8365
EnsemblGenome_TRS:
FBtr0084961
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0084335
RefSeq:
NP_524513.1
|
| Others |
UniRef100:
UniRef100_P13098
UniRef90:
UniRef90_P13098
UniRef50:
UniRef50_P13098
UniGene:
Dm.27416
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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