| Type | Description |
|---|---|
| Definition | MLLT3 super elongation complex subunit |
| Date | Results | Publications |
|---|---|---|
| 2020-09-05 13:54:00 | Characterization of Copy Number Variations in Oral Cavity Squamous Cell Carcinoma Reveals a Novel Role for MLLT3 in Cell Invasiveness. | 31273053 |
| 2020-04-04 11:39:00 | MLLT3 thus acts as haematopoietic stem cells (HSCs) maintenance factor that links histone reader and modifying activities to modulate HSC gene expressio | 31776511 |
| 2020-04-04 11:14:00 | Based on the observation that MLL-AF9 helps to preserve the ongoing gene expression program across multiple cellular contexts, study proposes that the rapidly proliferating, immature myeloid progenitor cell state initiates transformation when this cell state is perpetuated by MLL-AF9 expression, fulfilling the functional definition of malignancy. | 31852898 |
| 2020-02-08 10:18:00 | To study the ability of FLT3N676K to cooperate with KMT2A-MLLT3 in human leukemogenesis. | 30953031 |
| 2019-03-02 12:02:00 | This system provides for rapid systematic screening of relative risk, dose dependence, and combinatorial impact of multitudes of dietary and environmental exposures on MLL-AF9 translocations | 30387535 |
| Type | IDs |
|---|---|
| Synonymous | AF9, YEATS3 |
| Gene |
UniProtKB-ID:
AF9_HUMAN,
A0A0S2Z448_HUMAN
UniprotKB:
P42568,
A0A0S2Z448
UniParc:
UPI00019151E5,
UPI00002111CB
EMBL:
AK312914,
CH471071,
BC036089,
AL513498,
AL354879,
AL512635,
L13744,
KU178189,
AK301474,
AL163193,
AL627410
Ensembl:
ENSG00000171843
KO:
hsa:4300
|
| Nucleutide sequences |
EMBL-CDS:
EAW58632.1,
EAW58631.1,
AAH36089.1,
BAH13491.1,
BAG35760.1,
AAA58361.1,
ALQ33647.1
Ensembl_TRS:
ENST00000630269,
ENST00000380338
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000369695,
ENSP00000485996
RefSeq:
NP_004520.2,
XP_016870215.1,
NP_001273620.1,
XP_016870216.1
|
| Others |
UniRef100:
UniRef100_P42568
UniRef90:
UniRef90_P42568
UniRef50:
UniRef50_P42568
UniGene:
Hs.591085
CCDS:
CCDS69579.1,
CCDS6494.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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