| Type | Description |
|---|---|
| Definition | achaete-scute family bHLH transcription factor 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-18 11:20:00 | High ASCL2 expression is associated with colon cancer. | 31549316 |
| 2019-11-09 11:26:00 | Ascl2 negatively modulates pathogenic Th17cell differentiation via promoting IL-10 production, and alleviates intestinal inflammation. | 30722992 |
| 2019-11-02 10:32:00 | R-spondin1/Wnt activated Ascl2 expression dose-dependently in the CD133(+)CD44(+) colorectal cancer population. | 29886802 |
| 2019-08-10 10:17:00 | Study uncovers that SMYD3 controls Wnt induced activation of ASCL2 in cancer stem cells (CSCs) by regulating H3K4me3 status. These findings suggest that Wnt signals through a SMYD3-mediated epigenetic switch to promote ASCL2 expression and CSC maintenance in human gastric carcinoma (GC). Overexpression of SMYD3 and ASCL2 are associated with poor prognosis in GC patients. | 29746925 |
| 2019-08-10 10:03:00 | High ASCL2 expression is associated with Drug Resistance in Colorectal Cancer. | 30706227 |
| Type | IDs |
|---|---|
| Synonymous | ASH2, HASH2, MASH2, bHLHa45 |
| Gene |
UniProtKB-ID:
ASCL2_HUMAN
UniprotKB:
Q99929
UniParc:
UPI0000041179
EMBL:
AF442769,
BC136561,
BC057801,
U77629,
BC136567,
S82817
Ensembl:
ENSG00000183734
KO:
hsa:430
|
| Nucleutide sequences |
EMBL-CDS:
AAH57801.2,
AAL35362.1,
AAI36568.1,
AAB39362.1,
AAI36562.1,
AAB86993.1
Ensembl_TRS:
ENST00000331289
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000332293
RefSeq:
NP_005161.1
|
| Others |
UniRef100:
UniRef100_Q99929
UniRef90:
UniRef90_Q99929
UniRef50:
UniRef50_Q99929
UniGene:
Hs.152475
CCDS:
CCDS7732.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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