| Type | Description |
|---|---|
| Definition | AF4/FMR2 family member 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-10 12:58:00 | Osteopontin-c is overexpressed in KMT2A-AFF1 positive pediatric B-cell lymphoblastic leukemia when compared to those with ETV6-RUNX1"". | 32114371 |
| 2020-07-11 11:53:00 | The data indicates that AFF1 inhibits adipogenic differentiation by regulating the transcription of TGM2. | 32441391 |
| 2020-05-23 11:26:00 | we describe a functional and molecular cooperation between MA4 and A4M fusions during human hematopoietic development, and demonstrate how hESC-based hematopoietic differentiation represents a promising system to explore the developmental impact of the chimeric proteins resulting from chromosomal translocations, which remains obscure in human leukemia. | 30679325 |
| 2020-04-11 12:28:00 | the scaffold protein 14-3-3theta; enhances the aberrant activity of the chimeric transcription factor MLL-AF4 and, therefore, represents a new player in the molecular pathogenesis of t(4;11)-positive leukemia | 31493143 |
| 2018-06-16 10:39:00 | Our study represents the first report assessing the association of AFF1 rs340630 polymorphism with rheumatoid arthritis risk. No significant evidence was found for the dominant or recessive models. | 29791587 |
| Type | IDs |
|---|---|
| Synonymous | AF4, MLLT2, PBM1 |
| Gene |
UniProtKB-ID:
AFF1_HUMAN,
B4DJU9_HUMAN,
Q14C88_HUMAN
UniprotKB:
P51825,
B4DJU9,
Q14C88
UniParc:
UPI0000125658,
UPI00017A709B,
UPI000013EC58,
UPI000013EC52
EMBL:
BC114930,
CH471057,
AK296243,
AC093827,
L25050,
AC092658,
AC093779,
L13773,
AK300364
Ensembl:
ENSG00000172493
KO:
hsa:4299
|
| Nucleutide sequences |
EMBL-CDS:
BAG62103.1,
AAA36642.1,
AAA58360.1,
BAG58961.1,
EAX05979.1,
AAI14931.1
Gene_ORFName:
hCG_1816301
Ensembl_TRS:
ENST00000395146,
ENST00000307808
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000305689,
ENSP00000378578
RefSeq:
XP_016863705.1,
NP_001300889.1,
XP_005263066.1,
XP_005263068.1,
XP_005263064.1,
XP_005263070.1,
NP_001160165.1,
XP_016863704.1,
NP_005926.1,
XP_011530275.1,
NP_001300888.1
|
| Others |
UniRef100:
UniRef100_Q14C88,
UniRef100_P51825,
UniRef100_B4DJU9
UniRef90:
UniRef90_B4DJU9,
UniRef90_P51825
UniRef50:
UniRef50_P51825,
UniRef50_A0A5N4EHW6
UniGene:
Hs.480190
CCDS:
CCDS3616.1,
CCDS54775.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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