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42947 AstA

42947

AstA

Allatostatin A

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Allatostatin A

研究结论

Date Results Publications
2020-04-04 11:13:00 These data suggest that AstA/AstAR1 acts to coordinate juvenile growth with maturation. Interesting, AstA/AstAR1 is homologous to KISS/GPR54, a ligand-receptor signal required for human puberty, suggesting that an evolutionary conserved neural circuitry controls the onset of maturation. 30799245
2019-04-27 10:37:00 Midgut-preferential RNA knockdown of the peptide hormones AstA or Dh31 respectively results in decreased or increased adult lifespan. This effect on longevity is apparently correlated with the midgut senescence phenotypes as a result of direct hormone action through both hormone receptors expressed in the enteroblasts or other midgut cell types 29417892
2018-07-28 11:01:00 Va-A1 neurons terminally differentiate into DH31/AstA-expressing neurons (neuropeptidergic fate I) by virtue of Ubx activity, and Va-A2-A4 neurons terminally differentiate into Capa-expressing neurons 29634720

名称对应

Type IDs
Synonymous ALLS, AS, ASA, AST, AST-1, AST-3, AST-4, AST-A, Allatostatin A1, Allatostatin A2, Allatostatin A3, Allatostatin A4, Ast, Ast-A, AstA-1, AstA-2, AstA-3, AstA-4, BcDNA:RE16553, CG13633, DAP, DAP-A, DST-1A, DST-2A, DST-3A, DST-4A, Dmel\CG13633, Drm-AST-1, Drm-AST-2, Drm-AST-3, Drm-AST-4, Drm-AST-A, ast
Gene
UniProtKB-ID: ALLS_DROME, A0A0B4LHW3_DROME
UniprotKB: Q9VC44, A0A0B4LHW3
UniParc: UPI000012465F
EMBL: AE014297, KX531458, AY071110, AF263923
EnsemblGenome: FBgn0015591
KO: dme:Dmel_CG13633
Nucleutide sequences
EMBL-CDS: AAF56331.1, AAF97792.1, AAL48732.1, AHN57510.1, ANY27268.1
Gene_ORFName: CG13633, CG13633, Dmel_CG13633
EnsemblGenome_TRS: FBtr0346367, FBtr0084744, FBtr0084744, FBtr0346367
Protein sequencees
EnsemblGenome_PRO: FBpp0084119, FBpp0312068, FBpp0084119, FBpp0312068
RefSeq: NP_524489.2, NP_001287511.1
Others
UniRef100: UniRef100_Q9VC44
UniRef90: UniRef90_Q9VC44
UniRef50: UniRef50_Q9VC44
UniGene: Dm.1699

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