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4293 MAP3K9

4293

MAP3K9

mitogen-activated protein kinase kinase kinase 9

protein-coding

Homo sapiens

基因描述

Type Description
Definition mitogen-activated protein kinase kinase kinase 9

研究结论

Date Results Publications
2020-10-03 12:52:00 MicroRNA-148a regulates the MAPK/ERK signaling pathway and suppresses the development of esophagus squamous cell carcinoma via targeting MAP3K9. 31378889
2019-11-30 10:54:00 The overexpression of MAP3K9 could promote cell viability, migration and invasion rates, EMT process and ability of cloning, miR4905p could target MAP3K9 and further modulate the proliferation, migration, invasion and EMT of pharyngolaryngeal cancer cells. 31115491
2018-09-08 12:10:00 Data report that MKL1 was both sufficient and necessary for p65-dependent pro-inflammatory transcriptional program. MKL1 deficiency erased key histone modifications synonymous with transactivation on p65 target promoters. Specifically, MKL1 defined histone H3K4 trimethylation landscape for NF-kappaB dependent transcription. 28298643
2017-02-25 12:01:00 There was a negatively relationship between miR-15a and MAP3K9 expression in NP cells. 28081468
2016-10-01 12:33:00 miR148b directly targeted mitogenactivated protein kinase (MAPK) kinase kinase 9 (MAP3K9), an upstream activator of MAPK kinase/cJun Nterminal kinase (JNK) signaling, suppressing the protein but not the mRNA levels. 26573018

名称对应

Type IDs
Synonymous MEKK9, MLK1, PRKE1
Gene
UniProtKB-ID: M3K9_HUMAN, Q8NEB1_HUMAN, A0A087WW79_HUMAN, J3KPI6_HUMAN, B4DZC4_HUMAN, G3V347_HUMAN
UniprotKB: P80192, Q8NEB1, A0A087WW79, J3KPI6, B4DZC4, G3V347
UniParc: UPI00017A8591, UPI00021CF00E, UPI0000D62427, UPI000006F48C, UPI0003AE807F, UPI00021CF00F, UPI00001D7B5C
EMBL: AK302849, AF251442, AC004816, BC033197, AY327900, BC111407, BC133706
Ensembl: ENSG00000006432
KO: hsa:4293
Nucleutide sequences
EMBL-CDS: AAG44591.1, AAI33707.1, AAQ23054.1, AAI11408.1, AAH33197.1, BAG64036.1
Ensembl_TRS: ENST00000555993, ENST00000554752, ENST00000611979, ENST00000381250, ENST00000553414
Protein sequencees
Ensembl_PRO: ENSP00000451263, ENSP00000451612, ENSP00000480011, ENSP00000370649, ENSP00000451038
RefSeq: NP_001271160.1, XP_011535090.1, NP_001271159.1, NP_001271161.1, NP_149132.2, XP_005267740.1, XP_011535094.1, XP_011535096.1
Others
UniRef100: UniRef100_B4DZC4, UniRef100_A0A087WW79, UniRef100_Q8NEB1, UniRef100_J3KPI6, UniRef100_P80192
UniRef90: UniRef90_B4DZC4, UniRef90_A0A087WW79, UniRef90_A0A3Q1MHH5, UniRef90_M3W676, UniRef90_P80192
UniRef50: UniRef50_P80192, UniRef50_Q02779, UniRef50_H0XA78
UniGene: Hs.445496, Hs.593542
CCDS: CCDS32112.1, CCDS61488.1

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