| Type | Description |
|---|---|
| Definition | Tsc1 |
| Date | Results | Publications |
|---|---|---|
| 2016-12-17 10:52:00 | TSC1 is growth and size regulator, inhibit TOR-mediated amino acid availability to S6 kinase and translation initiation, its muscle and fat overactivation significantly extends lifespan. | 26318059 |
| 2014-04-26 10:15:00 | hyperactivation of TORC1 following the loss of TSC1/2 is detrimental to stem cell maintenance and multiple lineage differentiation in the Drosophila intestinal stem cell lineage, a mechanism that could be conserved in other stem cell lineages | 23843608 |
| 2013-11-30 10:47:00 | Data indicate that TORC1 activation by PVR involves Tsc1/Tsc2. | 23878397 |
| 2013-11-02 11:08:00 | deregulation of TORC1 induces activation of JNK, indicate that multiple cellular stresses are induced and contribute to the synthetic-lethal interactions between RB and TSC1/TSC2 inactivation. | 23447678 |
| 2012-12-08 10:02:00 | study demonstrates that in the Drosophila lymph gland the tumor suppressors TSC and PTEN control blood progenitor proliferation through a common TOR- and 4EBP-dependent pathway | 22951642 |
| Type | IDs |
|---|---|
| Synonymous | CG6147, Dmel\CG6147, TSC, TSC1, dTSC, dTSC-1, dTSC1, dTsc1, dtsc1, rocky, tsc1 |
| Gene |
UniProtKB-ID:
Q9VCC9_DROME
UniprotKB:
Q9VCC9
UniParc:
UPI00000752C4
EMBL:
AY118330,
AE014297
EnsemblGenome:
FBgn0026317
KO:
dme:Dmel_CG6147
|
| Nucleutide sequences |
EMBL-CDS:
AAF56240.1,
AAM48359.1
Gene_ORFName:
Dmel_CG6147,
CG6147
EnsemblGenome_TRS:
FBtr0084546
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0083931
RefSeq:
NP_477415.1
|
| Others |
UniRef100:
UniRef100_Q9VCC9
UniRef90:
UniRef90_Q9VCC9
UniRef50:
UniRef50_Q9VCC9
UniGene:
Dm.3097
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员