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42850 Atg6

42850

Atg6

Autophagy-related 6

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Autophagy-related 6

研究结论

Date Results Publications
2018-04-07 10:37:00 Atg6 is required for the inhibitory effect of metformin on intestinal stem cell aging. 29496445
2017-02-25 11:22:00 lowered expression of Atg6 or Pi3K59F in Ddc-Gal4-expressing neurons results in decreased longevity and associated age-dependent loss of locomotor ability. Inhibition of Atg6 or Pi3K59F together with overexpression of the sole pro-survival Bcl-2 Drosophila homolog Buffy in Ddc-Gal4-expressing neurons resulted in further decrease in the survival 27813607
2015-03-07 11:33:00 The UVRAG-containing PI3K (III) complex is required for receptor downregulation through endolysosomal degradation and for the establishment of proper cell polarity in the developing wing. 25006588
2013-05-04 11:37:00 Altered Atg6 function in flies causes hematopoietic abnormalities and lethality, and this is due to defects in multiple membrane trafficking processes. 23406899

名称对应

Type IDs
Synonymous ATG6, Beclin-1, Beclin1, CG5429, DmAtg6, Dmel\CG5429, atg6, beclin, dAtg6, l(3)00096
Gene
UniProtKB-ID: BECN1_DROME
UniprotKB: Q9VCE1
UniParc: UPI0000000E60
EMBL: AE014297, AY061424
EnsemblGenome: FBgn0264325
KO: dme:Dmel_CG5429
Nucleutide sequences
EMBL-CDS: AAL28972.1, AAF56227.1
Gene_ORFName: CG5429
EnsemblGenome_TRS: FBtr0084590
Protein sequencees
EnsemblGenome_PRO: FBpp0083975
RefSeq: NP_651209.1
Others
UniRef100: UniRef100_Q9VCE1
UniRef90: UniRef90_Q9VCE1
UniRef50: UniRef50_Q9VCE1
UniGene: Dm.20240

全选

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研究热度

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