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4281 MID1

4281

MID1

midline 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition midline 1

研究结论

Date Results Publications
2020-06-20 11:04:00 The expression levels of OSX and S100A4 correlated significantly in human breast tumors. 30450809
2019-06-08 10:42:00 TRAIL in serum and MID1 protein levels in biopsies from Idiopathic pulmonary fibrosis patients were increased compared to controls. TRAIL signalling through MID1 deactivates protein phosphatase 2A and promotes fibrosis with corresponding lung function decline. 30732588
2018-05-12 12:04:00 Data show that protein phosphatase-2A (PP2A) was upregulated in lung adenocarcinoma cell lines that were transfected with midline 1 E3 ubiquitin-protein ligase (MID1)-siRNA, suggesting MID1 negatively regulates PP2A in lung adenocarcinoma. 29450633
2018-02-24 10:26:00 identified four miRNAs, miR-19, miR-340, miR-374 and miR-542 that bind to the 3'-UTR of the MID1 mRNA. These miRNAs not only regulate MID1 expression but also mTOR signaling and translation of disease associated mRNAs and could therefore serve as potential drugs for future therapy development 29293623
2017-12-09 11:42:00 Our data reveal a novel role for MID1 and for atypical ubiquitination in balancing BRAF35 presence, and likely its activity, within nuclear and cytoplasmic compartments 28760657

名称对应

Type IDs
Synonymous BBBG1, FXY, GBBB1, MIDIN, OGS1, OS, OSX, RNF59, TRIM18, XPRF, ZNFXY
Gene
UniProtKB-ID: TRI18_HUMAN, A0A087X0X0_HUMAN, A0A024RBV4_HUMAN, A0A087X255_HUMAN
UniprotKB: O15344, A0A087X0X0, A0A024RBV4, A0A087X255
UniParc: UPI0000418A30, UPI000012F0E6, UPI000002ADF6, UPI0000D4BACB
EMBL: AK315095, CH471074, AF041206, AC008008, KC877957, AC002349, U96409, AF041210, AF230976, AF041207, AF041208, AF041209, BC053626, AF035360, AF269101, AC117406, AF230977, Y13667
Ensembl: ENSG00000101871
KO: hsa:4281
Nucleutide sequences
EMBL-CDS: AAC32999.1, AAC33001.1, AAC32998.1, CAA74018.1, AAC33002.1, AAG33130.1, AAG50191.1, AAG50192.1, AAC33000.1, BAG37559.1, AAH53626.1, AAB99951.1, EAW98780.1, EAW98781.1, EAW98779.1
Gene_ORFName: hCG_1811944
Ensembl_TRS: ENST00000380779, ENST00000380787, ENST00000380785, ENST00000380782, ENST00000453318, ENST00000317552, ENST00000380780, ENST00000610939, ENST00000616003
Protein sequencees
Ensembl_PRO: ENSP00000370156, ENSP00000414521, ENSP00000370157, ENSP00000312678, ENSP00000370164, ENSP00000370159, ENSP00000370162, ENSP00000483707, ENSP00000484712
RefSeq: NP_001180208.1, NP_000372.1, NP_001334662.1, NP_001180207.1, NP_001092094.1, NP_001180206.1, NP_150632.1, NP_150631.1, NP_001180209.1
Others
UniRef100: UniRef100_A0A087X0X0, UniRef100_O15344, UniRef100_A0A087X255
UniRef90: UniRef90_A0A2I3NEG2, UniRef90_O15344, UniRef90_A0A087X255
UniRef50: UniRef50_O15344, UniRef50_A0A2I3NEG2, UniRef50_A0A096MTA9
UniGene: Hs.27695, Hs.689953
CCDS: CCDS14138.1

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