| Type | Description |
|---|---|
| Definition | Iron regulatory protein 1A |
| Date | Results | Publications |
|---|---|---|
| 2020-03-14 11:37:00 | holo-IRP1A has a surprising new role in the nucleus, where it transcriptionally downregulates genes acting in steroid hormone biosynthesis as well as iron and heme metabolism. | 31784520 |
| 2010-01-21 00:00:00 | muscle-specific overexpression of IRP-1A, but not of IRP-1B, resulted in pre-adult lethality, underscoring the importance of the biochemical difference between the two proteins;only IRP-1A can bind to iron-responsive elements | 16679315 |
| Type | IDs |
|---|---|
| Synonymous | C-Acon, CG4900, Dmel\CG4900, IRF, IRP, IRP-1, IRP-1A, IRP1, c-Acon, cACON, cAcon, dIRP, irp1A |
| Gene |
UniProtKB-ID:
Q9VCV4_DROME
UniprotKB:
Q9VCV4
UniParc:
UPI000007ACD9
EMBL:
AY058657,
AE014297
EnsemblGenome:
FBgn0024958
KO:
dme:Dmel_CG4900
|
| Nucleutide sequences |
EMBL-CDS:
AAL13886.1,
AAF56051.1
Gene_ORFName:
CG4900,
Dmel_CG4900
EnsemblGenome_TRS:
FBtr0084327
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0083720
RefSeq:
NP_477371.1
|
| Others |
UniRef100:
UniRef100_Q9VCV4
UniRef90:
UniRef90_Q9VCV4
UniRef50:
UniRef50_P21399
UniGene:
Dm.3263
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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