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42646 Nrx-1

42646

Nrx-1

Neurexin 1

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Neurexin 1

研究结论

Date Results Publications
2019-12-14 10:51:00 Nrx functions with components of the BMP signaling pathway to ensure proper microtubule organization and axonal transport which is crucial for proper neuronal function. 30478335
2019-07-13 11:41:00 The authors find that axonal branch growth is regulated by dynamic, focal localisations of Neurexin and Neuroligin. These adhesion complexes provide stability for filopodia by a 'stick-and-grow' based mechanism wholly independent of synaptic activity. 29504935
2019-07-06 10:38:00 The disruption of DNlg1, DNlg2, or their presynaptic partner neurexin (DNrx) led to a dramatic decrease in the amount of F-actin. Further study showed that DNlg1, but not DNlg2 or DNlg3, directly interacts with the WRC via its C-terminal interacting receptor sequence. 29537369
2018-06-02 10:26:00 findings reveal that neurexin regulates nighttime sleep by mediating the synaptic transmission of alphabeta neurons. This study elucidates the role of synaptic transmission in sleep regulation, and might offer insights into the mechanism of sleep disturbances in patients with autism disorders. 27905548
2018-01-27 11:13:00 DNrx mutants have reduced levels of Wit. Dnrx is required for proper localization and stability of Wit. 27838296

名称对应

Type IDs
Synonymous CG7050, CT21808, DNrx, Dmel\CG7050, Nrx, Nrx1, dNrx, dnrx, dnrx-1, dnrx1, nrx, nrx-1, nrx1
Gene
UniProtKB-ID: Q3KN41_DROME, Q9VCZ9_DROME, A0A0B4KH61_DROME, A0A0B4KGQ3_DROME, A0A0B4KGL0_DROME
UniprotKB: Q3KN41, Q9VCZ9, A0A0B4KH61, A0A0B4KGQ3, A0A0B4KGL0
UniParc: UPI0002ADBCBC, UPI0000080DD4, UPI0002ADBCE4, UPI00005C8B89, UPI0002ADBCD8
EMBL: AE014297, BT023898
EnsemblGenome: FBgn0038975
KO: dme:Dmel_CG7050
Nucleutide sequences
EMBL-CDS: AGB96222.1, ABA81832.1, ACZ94983.1, AHN57466.1, AGB96218.1, AGB96217.1, AAF56006.1, AGB96221.1, AGB96219.1, AGB96220.1
Gene_ORFName: Dmel_CG7050, CG7050, CG7050, Dmel_CG7050, Dmel_CG7050, CG7050, Dmel_CG7050, CG7050, CG7050, Dmel_CG7050
EnsemblGenome_TRS: FBtr0334608, FBtr0345228, FBtr0334612, FBtr0301485, FBtr0334607, FBtr0084256, FBtr0334611, FBtr0334609, FBtr0334610
Protein sequencees
EnsemblGenome_PRO: FBpp0311420, FBpp0306675, FBpp0306679, FBpp0290700, FBpp0083649, FBpp0306674, FBpp0306678, FBpp0306676, FBpp0306677
RefSeq: NP_001262839.1, NP_001262838.1, NP_524449.1, NP_001262840.1, NP_001287467.1, NP_001262842.1, NP_001163687.1, NP_001262837.1, NP_001262841.1
Others
UniRef100: UniRef100_Q9VCZ9, UniRef100_A0A0B4KH61, UniRef100_A0A0B4KGL0, UniRef100_Q3KN41, UniRef100_A0A0B4KGQ3
UniRef90: UniRef90_Q9VCZ9, UniRef90_A0A0B4KH61
UniRef50: UniRef50_Q9VCZ9
UniGene: Dm.1980

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研究热度

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