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4257 MGST1

4257

MGST1

microsomal glutathione S-transferase 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition microsomal glutathione S-transferase 1

研究结论

Date Results Publications
2020-06-06 13:13:00 MGST1 plays an important role in lung adenocarcinoma (LUAD)tumorigenesis and might serve as a potential prognostic factor and therapeutic target in LUAD. 31707341
2018-10-27 11:06:00 High MGST1 expression is associated with Bendamustine-resistance in Mantle Cell Lymphoma. 29695404
2018-08-04 10:06:00 Significant association for germline variations only in the COX pathway (specifically in the antioxidant microsomal glutathione S-transferase 1 [MGST1] gene), with risk for Barrett's esophagus and the combined outcome of Barrett's esophagus and esophageal adenocarcinoma was found. 29713984
2017-09-30 12:57:00 This study provides the most comprehensive evaluation of inflammation-related germline variation in relation to risk of BE/OA and suggests that variants in MGST1 influence disease susceptibility. 27486097
2017-09-30 10:58:00 The MSGT1 displays a preexisting dynamic equilibrium between high- and low-activity forms. 28558199

名称对应

Type IDs
Synonymous GST12, MGST, MGST-I
Gene
UniProtKB-ID: MGST1_HUMAN, A0A024RAX2_HUMAN
UniprotKB: P10620, A0A024RAX2
UniParc: UPI0000036C19, UPI00001FB707
EMBL: U71212, AY368173, AC007552, AC007529, BT006982, BC005923, AK291148, U46497, AC007528, U71213, U46498, AF092926, U71211, BC056863, CH471094, J03746
Ensembl: ENSG00000008394
KO: hsa:4257
Nucleutide sequences
EMBL-CDS: AAB17184.1, AAC50711.1, AAQ55111.1, EAW96367.1, AAA35934.1, AAH05923.1, EAW96362.1, BAF83837.1, AAP35628.1, EAW96369.1, EAW96366.1
Gene_ORFName: hCG_25167
Ensembl_TRS: ENST00000396209, ENST00000010404, ENST00000396207, ENST00000535309, ENST00000396210
Protein sequencees
Ensembl_PRO: ENSP00000379513, ENSP00000010404, ENSP00000379512, ENSP00000379510, ENSP00000438308
RefSeq: NP_001247441.1, XP_011518975.1, NP_001247440.1, NP_665735.1, NP_665734.1, XP_011518976.1, NP_064696.1, NP_001254527.1, NP_665707.1, XP_006719142.1
Others
UniRef100: UniRef100_P10620
UniRef90: UniRef90_P10620
UniRef50: UniRef50_P10620
UniGene: Hs.389700
CCDS: CCDS8677.1, CCDS58209.1

全选

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