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42549 InR

42549

InR

Insulin-like receptor

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Insulin-like receptor

研究结论

Date Results Publications
2020-07-11 12:11:00 Lar physically associates with InR and serves as a negative regulator for insulin signaling in the Drosophila larval hematopoietic niche. 31784462
2020-03-14 10:49:00 The authors reveal that transient activation of JNK enhances the expression of the insulin receptor and initiates the insulin-Myc signaling loop to promote mitochondrial respiration and biogenesis by boosting the expression of electron transport chain subunits and of factors essential for mtDNA replication and expression, and for the import of mitochondrial proteins. 31612862
2019-12-07 11:28:00 Rab6 promotes localization of the insulin receptor to the plasma membrane. 30111579
2019-09-21 11:27:00 Hsp83 functions upstream of the InR/PI3K/Akt pathway during neural stem cell reactivation. 30245208
2018-12-22 10:28:00 Immunosenescence in Drosophila suggests its possible mechanisms that involve changes in insulin/IGF-1 signaling. (Review) 30134574

名称对应

Type IDs
Synonymous 18402, CG18402, DIHR, DILR, DIR, DIRH, DIRbeta, DInR, DInr, Dir-a, Dir-b, Dmel\CG18402, INR, INS, IR, Inr, Inr-alpha, Inr-beta, InsR, dINR, dINSR, dIR, dIRH, dInR, dInr, dInsR, dinr, dir, er10, inR, inr, insulin/insulin-like growth factor receptor, l(3)05545, l(3)93Dj, l(3)er10, lnR, sprout
Gene
UniProtKB-ID: INSR_DROME
UniprotKB: P09208
UniParc: UPI000007DE09
EMBL: U18351, AE014297, M13568, U28136, M14778
EnsemblGenome: FBgn0283499
KO: dme:Dmel_CG18402
Nucleutide sequences
EMBL-CDS: AAA28645.1, ACL83549.1, ACL83550.1, AAC47458.1, AAA28644.1, ACL83551.1, AAA68953.1, AAF55903.2
Gene_ORFName: CG18402
EnsemblGenome_TRS: FBtr0290230, FBtr0290232, FBtr0290231, FBtr0084121
Protein sequencees
EnsemblGenome_PRO: FBpp0288669, FBpp0288670, FBpp0288671, FBpp0083519
RefSeq: NP_524436.2, NP_001138093.1, NP_001138095.1, NP_001138094.1
Others
UniRef100: UniRef100_P09208
UniRef90: UniRef90_P09208
UniRef50: UniRef50_P09208
UniGene: Dm.1271

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