| Type | Description |
|---|---|
| Definition | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:32:00 | Recognition of glycan and protein substrates by N-acetylglucosaminyltransferase-V. | 32890705 |
| 2019-05-11 11:49:00 | Results suggest increased post-translational modification of RPTPmu N-glycans by GnT-V attenuates its tyrosine phosphatase activity and promotes glioma cell migration through pathways. | 30274773 |
| 2019-01-19 11:49:00 | GnT-V enhances gemcitabine chemosensitivity via modulation of human ENT1 N-glycosylation and transport activity in T24cells, providing new insights into how N-glycosylation drives antitumor drug sensitivity during chemotherapy for patients with cancer. | 30143259 |
| 2019-01-19 11:01:00 | The acceptor-GnT-V complex structure suggests a catalytic mechanism, explains the previously observed inhibition of GnT-V by branching enzyme GnT-III, and provides a basis for the rational design of drugs targeting N-glycan branching. | 30140003 |
| 2018-01-20 11:45:00 | The best homology model is consistent with available experimental data. The three-dimensional model, the structure of the enzyme catalytic site and binding information obtained for the donor and acceptor can be useful in studies of the catalytic mechanism and design of inhibitors of GnT-V. | 26821880 |
| Type | IDs |
|---|---|
| Synonymous | GNT-V, GNT-VA, MGAT5A |
| Gene |
UniProtKB-ID:
MGT5A_HUMAN
UniprotKB:
Q09328
UniParc:
UPI0000049D8F
EMBL:
D17716,
CH471058,
AF113921
Ensembl:
ENSG00000152127
KO:
hsa:4249
|
| Nucleutide sequences |
EMBL-CDS:
BAA04570.1,
EAX11658.1,
AAD22449.1,
EAX11657.1
Ensembl_TRS:
ENST00000409645,
ENST00000281923
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000386377,
ENSP00000281923
RefSeq:
XP_005263726.1,
XP_011509504.1,
NP_001358386.1,
XP_016859638.1,
XP_011509506.1,
XP_011509503.1,
XP_005263727.1,
XP_016859637.1,
NP_002401.1,
XP_011509501.1,
XP_011509502.1,
XP_006712597.1,
XP_016859636.1
|
| Others |
UniRef100:
UniRef100_Q09328
UniRef90:
UniRef90_Q09328
UniRef50:
UniRef50_Q09328
UniGene:
Hs.4988
CCDS:
CCDS2171.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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