| Type | Description |
|---|---|
| Definition | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase |
| Date | Results | Publications |
|---|---|---|
| 2020-05-23 12:40:00 | Study found that N-Acetylglucosaminyltransferase III (GnT-III) is expressed in trophoblasts during normal human pregnancy and is involved in regulating trophoblast function. | 29642803 |
| 2019-10-19 10:25:00 | The expression of GnT-III in placenta suggests a role for GnT-III in the regulation of tropho- blast behavior. And decreased expression of GnT-III is associated with oxidative stress in preeclamptic pla- centas and, thus, may be involved in the pathogenesis of preeclampsia. | 29466889 |
| 2019-05-25 10:10:00 | Results strongly indicate that the MGAT3 and BACH2 genes play an important role in IBD pathogenesis and suggest a possible disease pathway mediated by the pro-inflammatory properties of IgG antibodies acquired by alterations in Fc glycosylation. | 29991969 |
| 2018-02-10 11:14:00 | Novel insights into the epigenetic regulation of MGAT3/bisecting GlcNAc and demonstrate the importance of N-glycosylation in cancer progression. | 27429195 |
| 2017-10-21 11:52:00 | Data suggest that GNT-III expression regulates levels/activation of the heavily glycosylated Notch receptor involved in normal and malignant cell development; suppression of GNT-III in epithelial ovarian carcinoma cell lines results in down-regulation of Notch signaling that is more potent than pharmacologic blockage of Notch activation. | 28842505 |
| Type | IDs |
|---|---|
| Synonymous | GNT-III, GNT3 |
| Gene |
UniProtKB-ID:
MGAT3_HUMAN
UniprotKB:
Q09327
UniParc:
UPI00003765B6
EMBL:
BC113718,
D13789,
AL022312,
CR456519,
BC113383,
BC075026,
BC075025
Ensembl:
ENSG00000128268
KO:
hsa:4248
|
| Nucleutide sequences |
EMBL-CDS:
AAH75025.1,
AAI13384.1,
CAG30405.1,
BAA02937.1,
AAI13719.1,
AAH75026.1
Ensembl_TRS:
ENST00000341184
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000345270
RefSeq:
NP_001091740.1,
NP_002400.3
|
| Others |
UniRef100:
UniRef100_Q09327
UniRef90:
UniRef90_Q09327
UniRef50:
UniRef50_Q10470
UniGene:
Hs.276808
CCDS:
CCDS13994.2
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| 1 |
Institute of Molecular Biomembrane and Glycobiology |
3 |
| 2 |
Osaka University Medical School |
3 |
| 3 |
Osaka University Graduate School of Medicine |
2 |
| 4 |
Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP) |
2 |
| 5 |
Chongqing Medical University |
2 |
| 排名 | 研究人员 | 文献 |
|---|---|---|
| 1 |
Tomoya Isaji |
5 |
| 2 |
Jianguo Gu |
5 |
| 3 |
Naoyuki Taniguchi |
5 |
| 4 |
Gordan Lauc |
3 |
| 5 |
Koichi Honke |
3 |