| Type | Description |
|---|---|
| Definition | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| Date | Results | Publications |
|---|---|---|
| 2018-09-01 12:14:00 | The recombinant hGnTII was purified from silkworm larval hemolymph in two steps by using tandem affinity purification tags, with a yield of approximately 120 mug from 10 mL hemolymph, and exhibited glycosyltransferase activity and strict substrate specificity. The enzyme was found to be N-glycosylated by the enzymatic cleavage of glycans, while hGnTII expressed in insect cells had not been reported to be glycosylated. | 29409697 |
| 2018-08-18 12:05:00 | These data suggest that substrate binding by MGAT2 employs both conserved and convergent catalytic subsite modules to provide substrate selectivity and catalysis. More broadly, the MGAT2 active-site architecture demonstrates how glycosyltransferases create complementary modular templates for regiospecific extension of glycan structures in mammalian cells. | 29666272 |
| 2016-02-27 11:16:00 | UDP-galactose (SLC35A2) and UDP-N-acetylglucosamine (SLC35A3) Transporters Form Glycosylation-related Complexes with Mannoside Acetylglucosaminyltransferases (Mgats). | 25944901 |
| 2010-06-28 11:07:00 | Golgi N-glycosyltransferases beta-1,2-N-acetylglucosaminyltransferase I, beta-1,2-N-acetylglucosaminyltransferase II, 1,4-galactosyltransferase I, and alpha-2,6-sialyltransferase I form both homo- and heterodimeric enzyme complexes in live cells | 20378551 |
| Type | IDs |
|---|---|
| Synonymous | CDG2A, CDGS2, GLCNACTII, GNT-II, GNT2 |
| Gene |
UniProtKB-ID:
MGAT2_HUMAN
UniprotKB:
Q10469
UniParc:
UPI000012B8CA
EMBL:
CH471078,
AK075199,
U15128,
BC006390,
AK056167
Ensembl:
ENSG00000168282
KO:
hsa:4247
|
| Nucleutide sequences |
EMBL-CDS:
AAA86956.1,
BAG51637.1,
EAW65758.1,
BAG52082.1,
AAH06390.1
Ensembl_TRS:
ENST00000305386
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000307423
RefSeq:
NP_002399.1
|
| Others |
UniRef100:
UniRef100_Q10469
UniRef90:
UniRef90_Q10469
UniRef50:
UniRef50_Q10469
UniGene:
Hs.93338
CCDS:
CCDS9690.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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