Type | Description |
---|---|
Definition | mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
Date | Results | Publications |
---|---|---|
2021-02-20 13:36:00 | Point mutations that inactivate MGAT4D-L, an inhibitor of MGAT1 and complex N-glycan synthesis. | 32763972 |
2020-07-25 11:39:00 | MGAT1 promotes complex N-glycosylation of glucose transporter 1 (Glut1) and increases Glut1 protein levels. In summary, our findings indicate that MGAT1 is highly expressed in glioblastoma and promotes glioma cells at least partly through upregulation of Glut1 protein. | 31494931 |
2019-09-14 10:52:00 | MGAT1 activity may play a role in regulating basal adipocyte FFA retention | 29853530 |
2018-08-11 11:34:00 | In this study we showed that the activation of Wnt/beta-catenin pathway culminates in the upregulation of MGAT1 enzyme both at transcriptional and post-transcriptional levels. We also showed that overexpression of the beta-catenin gene (CTNNB1) increased the promoter activity of MGAT1. | 29310626 |
2018-01-13 10:03:00 | The presence of the rs4285184 polymorphism of the MGAT1 gene increased the risk for developing body fat associated with obesity in the Mexican population. | 27871764 |
Type | IDs |
---|---|
Synonymous | GLCNAC-TI, GLCT1, GLYT1, GNT-1, GNT-I, GnTI, MGAT |
Gene |
UniProtKB-ID:
MGAT1_HUMAN
UniprotKB:
P26572
UniParc:
UPI000013CDF1
EMBL:
CH471165,
AK092256,
AK290769,
AK094130,
M55621,
AC022413,
M61829,
CR456861,
BC003575
Ensembl:
ENSG00000131446
KO:
hsa:4245
|
Nucleutide sequences |
EMBL-CDS:
EAW53742.1,
BAG52510.1,
EAW53740.1,
EAW53739.1,
BAF83458.1,
CAG33142.1,
AAA75523.1,
AAH03575.1,
EAW53743.1,
BAG52821.1,
AAA52563.1,
EAW53741.1,
EAW53744.1
Ensembl_TRS:
ENST00000393340,
ENST00000333055,
ENST00000307826,
ENST00000446023,
ENST00000427865
|
Protein sequencees |
Ensembl_PRO:
ENSP00000377010,
ENSP00000402838,
ENSP00000332073,
ENSP00000311888,
ENSP00000404718
RefSeq:
NP_001351320.1,
NP_001351315.1,
NP_001351322.1,
NP_001108092.1,
NP_001351313.1,
NP_001351318.1,
NP_001351316.1,
NP_001351323.1,
NP_001108090.1,
NP_002397.2,
NP_001351314.1,
NP_001351308.1,
NP_001351317.1,
NP_001351306.1,
NP_001351324.1,
NP_001108091.1,
NP_001108089.1,
NP_001351310.1,
NP_001351321.1,
NP_001351312.1,
NP_001351311.1,
NP_001351309.1,
NP_001351319.1
|
Others |
UniRef100:
UniRef100_P26572
UniRef90:
UniRef90_P26572
UniRef50:
UniRef50_P26572
UniGene:
Hs.519818
CCDS:
CCDS4458.1
|
排名 | 科研单位 | 文献 |
---|---|---|
1 |
Albert Einstein College of Medicine |
4 |
2 |
Research Institute |
3 |
3 |
Helix Research Institute |
2 |
4 |
Uppsala University |
2 |
5 |
Ontario Cancer Institute |
2 |
排名 | 研究人员 | 文献 |
---|---|---|
1 |
Sumio Sugano |
5 |
2 |
Yutaka Suzuki |
5 |
3 |
Riu Yamashita |
3 |
4 |
Kenta Nakai |
3 |
5 |
Keiichi Nagai |
3 |